Evidence map›Paper›PMID 28082828›Full record

ArticleJournal of child & adolescent substance abuse2016

Pharmacotherapy for Substance Use Disorders in Youths.

Christopher J Hammond, Kevin M Gray

Abstract read
In one paragraph

Article in Journal of child & adolescent substance abuse, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 17 citations in OpenAlex.

  1. Medications for Opioid Use Disorder for Youth: Patient, Caregiver, and Clinician Perspectives.The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2024
    Article
  2. Article
  3. Saliva DNA Methylation Detects Nascent Smoking in Adolescents.Journal of child and adolescent psychopharmacology · 2019
    Article
  4. Research Review: What have we learned about adolescent substance use?Journal of child psychology and psychiatry, and allied disciplines · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Christopher J HammondYale Child Study Center, New Haven, CT, USA.
Kevin M GrayMedical University of South Carolina, Charleston, SC, USA.
Johns Hopkins University · USMedical University of South Carolina · US

Funding

Southern Consortium Node of the Clinical Trials NetworkU10DA013727 · NIDA · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI BRADY, KATHLEEN T. · 2000 to 2015
$34.4M
AACAP Physician Scientist Program in Substance UseK12DA000357 · NIDA · AMERICAN ACADEMY-CHILD/ADOLESCENT PSYCH · PI Kevin M. Gray · 1998 to 2026
$29.1M
A Randomized Controlled Trial of Varenicline for Adolescent Smoking CessationU01DA031779 · NIDA · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI GRAY, KEVIN M · 2012 to 2016
$3.3M
A Controlled Trial of N-Acetylcysteine (NAC) in Cannabis Dependent AdolescentsR01DA026777 · NIDA · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI GRAY, KEVIN M · 2009 to 2010
$722k
NIDA NIH HHS K12 DA000357NIDA NIH HHS R01 DA026777NIDA NIH HHS U01 DA031779NIDA NIH HHS U10 DA013727
6 · The paper itself

Abstract

Despite recent advances in psychosocial treatments targeting adolescent substance use disorders (SUD), effect sizes generally remain small to modest, and few treatment-enrolled youth achieve sustained abstinence. Among adults, SUD-targeted pharmacotherapies have emerged as viable options to complement psychosocial treatments and enhance outcomes. Developmental differences exist in pharmacodynamics and treatment-response, and comparatively little research has focused on SUD-targeted pharmacotherapies for youth. This article provides a review and synthesis of relevant published clinical trials focusing on youth SUDs and co-occurring/comorbid psychiatric and substance use disorders. It offers recommendations for clinical practice and further research based on the limited findings to date.

Indexed as

adolescencepharmacotherapysubstance use disordersyouth

Identifiers

PMID28082828
PMCPMC5222569
OpenAlexW2336658191

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.