Evidence map›Paper›PMID 28082681›Full record

ArticleThe Journal of biological chemistry2017

A Positive Amplification Mechanism Involving a Kinase and Replication Initiation Factor Helps Assemble the Replication Fork Helicase.

Irina Bruck, Nalini Dhingra, Daniel L Kaplan

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of biological chemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
  3. Cryo-EM structure of Mcm2-7 double hexamer on DNA suggests a lagging-strand DNA extrusion model.Proceedings of the National Academy of Sciences of the United States of America · 2017
    Article
  4. Single-molecule visualization ofProceedings of the National Academy of Sciences of the United States of America · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Irina BruckDepartment of Biomedical Sciences, Florida State University College of Medicine, Tallahassee, Florida 32306.
Nalini DhingraDepartment of Biomedical Sciences, Florida State University College of Medicine, Tallahassee, Florida 32306.
Daniel L KaplanDepartment of Biomedical Sciences, Florida State University College of Medicine, Tallahassee, Florida 32306. Electronic address: Daniel.Kaplan@med.fsu.edu.
Florida State University · US

Funding

Assembly and Activation of the Eukaryotic Replication Fork HelicaseR15GM113167 · NIGMS · FLORIDA STATE UNIVERSITY · PI KAPLAN, DANIEL L · 2015 to 2015
$360k
NIGMS NIH HHS R15 GM113167
6 · The paper itself

Abstract

The assembly of the replication fork helicase during S phase is key to the initiation of DNA replication in eukaryotic cells. One step in this assembly in budding yeast is the association of Cdc45 with the Mcm2-7 heterohexameric ATPase, and a second step is the assembly of the tetrameric GINS (

Indexed as

DNA ReplicationCell Cycle ProteinsDNA, FungalFungal ProteinsMinichromosome Maintenance ProteinsPhosphorylationProtein Serine-Threonine KinasesSaccharomycetalesCell Cycle ProteinsDNA, FungalFungal ProteinsMinichromosome Maintenance ProteinsProtein Serine-Threonine Kinasescell cycleDNA helicaseDNA-protein interactionDNA replicationphosphorylation

Identifiers

PMID28082681
PMCPMC5336144
OpenAlexW2574656246

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.