Evidence map›Paper›PMID 28082422›Full record

ArticleJournal of cell science2017

Suppression of intestinal tumorigenesis in

Andy R Wolfe, Amanda Ernlund, William McGuinness, Carl Lehmann, Kaitlyn Carl, Nicole Balmaceda, Kristi L Neufeld

RetractedOpen access · bronzeAbstract readRetracted Publication
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of cell science, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Andy R WolfeDepartment of Molecular Biosciences, University of Kansas, 7049 Haworth Hall, 1200 Sunnyside Ave., Lawrence, KS 66045, USA.
Amanda ErnlundDepartment of Molecular Biosciences, University of Kansas, 7049 Haworth Hall, 1200 Sunnyside Ave., Lawrence, KS 66045, USA.
William McGuinnessDepartment of Molecular Biosciences, University of Kansas, 7049 Haworth Hall, 1200 Sunnyside Ave., Lawrence, KS 66045, USA.
Carl LehmannDepartment of Molecular Biosciences, University of Kansas, 7049 Haworth Hall, 1200 Sunnyside Ave., Lawrence, KS 66045, USA.ORCID 0000-0001-6905-4195
Kaitlyn CarlDepartment of Molecular Biosciences, University of Kansas, 7049 Haworth Hall, 1200 Sunnyside Ave., Lawrence, KS 66045, USA.ORCID 0000-0001-6197-4173
Nicole BalmacedaDepartment of Molecular Biosciences, University of Kansas, 7049 Haworth Hall, 1200 Sunnyside Ave., Lawrence, KS 66045, USA.ORCID 0000-0002-9670-5907
Kristi L NeufeldDepartment of Molecular Biosciences, University of Kansas, 7049 Haworth Hall, 1200 Sunnyside Ave., Lawrence, KS 66045, USA klneuf@ku.edu.ORCID 0000-0003-3653-9385
University of Kansas · US

Funding

Mentoring CoreP20GM103418 · NIGMS · UNIVERSITY OF KANSAS MEDICAL CENTER · PI Douglas E Wright · 2012 to 2026
$63.0M
Transgenic & Gene-Targeting Shared ResourceP30CA168524 · NCI · UNIVERSITY OF KANSAS MEDICAL CENTER · PI ROY A. JENSEN · 2012 to 2026
$40.1M
Small molecules modulating RNA-binding protein Msi1R01CA178831 · NCI · UNIVERSITY OF KANSAS LAWRENCE · PI NEUFELD, KRISTI L, XU, LIANG · 2014 to 2016
$1.3M
NCI NIH HHS P30 CA168524NCI NIH HHS R01 CA178831NIGMS NIH HHS P20 GM103418
6 · The paper itself

Abstract

Therapeutic strategies based on a specific oncogenic target are better justified when elimination of that particular oncogene reduces tumorigenesis in a model organism. One such oncogene, Musashi-1 (

Indexed as

Gene DeletionAdenomatous Polyposis ColiAnimalsCarcinogenesisCell CountCell ProliferationColonic PolypsDisease Models, AnimalEpitheliumIntestinal NeoplasmsIntestine, SmallMiceMice, Mutant StrainsNerve Tissue ProteinsReceptors, NotchRNA-Binding ProteinsMsi1h protein, mouseNerve Tissue ProteinsReceptors, NotchRNA-Binding ProteinsAdenomatous polyposis coliApcIntestinal tumorigenesisMsi-1Musashi-1NotchWnt

Identifiers

PMID28082422
PMCPMC5339888
OpenAlexW2575975250

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.