Evidence map›Paper›PMID 28082314›Full record

ArticleEMBO reports2017

A

Myriam Bourens, Antoni Barrientos

Open access · bronzeAbstract read
In one paragraph

Article in EMBO reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 67 citations in OpenAlex.

  1. Review
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  13. Cytotoxic CD8Frontiers in immunology · 2024
    Article
  14. Article
  15. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Myriam BourensDepartment of Neurology, University of Miami Miller School of Medicine, Miami, FL, USA.
Antoni BarrientosDepartment of Neurology, University of Miami Miller School of Medicine, Miami, FL, USA abarrientos@med.miami.edu.ORCID 0000-0001-9018-3231
University of Miami · US

Funding

Mitochondrial Biogenesis in Health and DiseaseR35GM118141 · NIGMS · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI BARRIENTOS, ANTONI · 2016 to 2025
$8.9M
CYTOCHROME C OXIDASE IN HEALTH AND DISEASER01GM071775 · NIGMS · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI BARRIENTOS, ANTONI · 2006 to 2015
$3.1M
The Biosynthetic Pathway of Mitochondrial RespirasomesR01GM105781 · NIGMS · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI BARRIENTOS, ANTONI · 2014 to 2016
$894k
Biogenesis of the Mitochondrial Translation MachineryR01GM112179 · NIGMS · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI BARRIENTOS, ANTONI · 2015 to 2016
$584k
NIGMS NIH HHS R01 GM071775NIGMS NIH HHS R01 GM105781NIGMS NIH HHS R01 GM112179NIGMS NIH HHS R35 GM118141
6 · The paper itself

Abstract

Defects in mitochondrial respiratory chain complex IV (CIV) frequently cause encephalocardiomyopathies. Human CIV assembly involves 14 subunits of dual genetic origin and multiple nucleus-encoded ancillary factors. Biogenesis of the mitochondrion-encoded copper/heme-containing COX1 subunit initiates the CIV assembly process. Here, we show that the intermembrane space twin CX

Indexed as

Protein BiosynthesisAllelesCyclooxygenase 1Electron Transport Complex IVEnzyme StabilityGene Knockout TechniquesHEK293 CellsHumansMembrane ProteinsMitochondriaMitochondrial ProteinsModels, BiologicalMultiprotein ComplexesProtein BindingProtein Processing, Post-TranslationalTranscription Activator-Like Effector NucleasesCyclooxygenase 1Electron Transport Complex IVMembrane ProteinsMitochondrial ProteinsMultiprotein ComplexesTranscription Activator-Like Effector NucleasesCMC1complex IVCOX1cytochrome c oxidasemitochondrial respiratory chain

Identifiers

PMID28082314
PMCPMC5331208
OpenAlexW2573237857

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.