Evidence map›Paper›PMID 28081305›Full record

ArticleAdvanced healthcare materials2017

Biocompatible Multifunctional Black-Silicon for Implantable Intraocular Sensor.

Jeong Oen Lee, Vinayak Narasimhan, Juan Du, Blaise Ndjamen, David Sretavan, Hyuck Choo

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Advanced healthcare materials, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Article
  6. A microscale optical implant for continuousMicrosystems & nanoengineering · 2017
    Article
  7. Real-TimeIEEE sensors journal
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jeong Oen LeeDepartment of Medical Engineering, California Institute of Technology, Pasadena, CA, 91106, USA.
Vinayak NarasimhanDepartment of Medical Engineering, California Institute of Technology, Pasadena, CA, 91106, USA.
Juan DuDepartment of Ophthalmology, University of California, San Francisco, San Francisco, CA, 94143, USA.
Blaise NdjamenDepartment of Medical Engineering, California Institute of Technology, Pasadena, CA, 91106, USA.
David SretavanDepartment of Ophthalmology, University of California, San Francisco, San Francisco, CA, 94143, USA.
Hyuck ChooDepartment of Medical Engineering, California Institute of Technology, Pasadena, CA, 91106, USA.

Funding

Rapid-Prototyping and Design CoreP30EY002162 · NEI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI LAKKARAJU, APARNA · 1985 to 2024
$16.8M
Intraocular Pressure Sensing Using LightR01EY024582 · NEI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CHOO, HYUCK, SRETAVAN, DAVID W · 2016 to 2018
$989k
NEI NIH HHS R01 EY024582
6 · The paper itself

Abstract

Multifunctional black-silicon (b-Si) integrated on the surface of an implantable intraocular pressure sensor significantly improves sensor performance and reliability in six-month in vivo studies. The antireflective properties of b-Si triples the signal-to-noise ratio and increases the optical readout distance to a clinically viable 12 cm. Tissue growth and inflammation response on the sensor is suppressed demonstrating desirable anti-biofouling properties.

Indexed as

Implants, ExperimentalIntraocular PressureMaterials TestingSiliconTonometry, OcularAnimalsRabbitsSiliconblack-siliconglaucomaintraocular pressurein vivo monitoringoptical readout

Identifiers

PMID28081305
PMCPMC5522682

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.