Evidence map›Paper›PMID 28081298›Full record

ArticleAdvanced healthcare materials2017

Full-Thickness Heart Repair with an Engineered Multilayered Myocardial Patch in Rat Model.

Seokwon Pok, Igor V Stupin, Christopher Tsao, Robia G Pautler, Yang Gao, Raymond M Nieto, Ze-Wei Tao, Charles D Fraser, Ananth V Annapragada, Jeffrey G Jacot

Open access · greenAbstract read
In one paragraph

Article in Advanced healthcare materials, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.

  1. Pooled it
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  7. AnMaterials today. Communications · 2023
    Article
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  13. Current advances in biodegradable synthetic polymer based cardiac patches.Journal of biomedical materials research. Part A · 2020
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Seokwon PokDepartment of Bioengineering, Rice University, Houston, TX 77005, USA.
Igor V StupinDepartment of Basic Radiology Research, Texas Children's Hospital, Houston, TX 77030, USA.
Christopher TsaoDepartment of Bioengineering, Rice University, Houston, TX 77005, USA.
Robia G PautlerDepartment of Molecular Physiology, Baylor College of Medicine, Houston, TX 77030, USA.
Yang GaoDepartment of Bioengineering, Rice University, Houston, TX 77005, USA.
Raymond M NietoDivision of Congenital Heart Surgery, Texas Children's Hospital, Houston, TX 77030, USA.
Ze-Wei TaoDepartment of Bioengineering, University of Colorado Denver/Anschutz Medical Campus, Aurora, CO 80045, USA.
Charles D FraserDivision of Congenital Heart Surgery, Texas Children's Hospital, Houston, TX 77030, USA.
Ananth V AnnapragadaDepartment of Basic Radiology Research, Texas Children's Hospital, Houston, TX 77030, USA.
Jeffrey G JacotDepartment of Bioengineering, Rice University, Houston, TX 77005, USA.
Texas Children's Hospital · USRice University · USBaylor College of Medicine · USUniversity of Colorado Anschutz Medical Campus · US

Funding

PRE-VASCULARIZED AND DEGRADABLE PATCHES FOR CORRECTION OF CONGENITAL HEART DEFECTSR01HL130436 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI JACOT, JEFFREY G · 2016 to 2020
$2.0M
NHLBI NIH HHS R01 HL130436
6 · The paper itself

Abstract

In a rat model of right free wall replacement, the transplantation of an engineered multilayered myocardial patch fabricated from a polycaprolactone membrane supporting a chitosan/heart matrix hydrogel induces significant muscular and vascular remodeling and results in a significantly higher right ventricular ejection fraction compared to use of a commercially available pericardium patch.

Indexed as

ChitosanHydrogelsMaterials TestingMembranes, ArtificialMyocardiumPericardiumAnimalsDisease Models, AnimalFemaleMalePolyestersRatsRats, Sprague-DawleyChitosanHydrogelsMembranes, ArtificialpolycaprolactonePolyesterschitosancongenital heart defectsheart patchpolycaprolactoneright ventricular outflow tract

Identifiers

PMID28081298
PMCPMC5896558
OpenAlexW2579575406

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.