Evidence map›Paper›PMID 28081046›Full record

ArticleSexually transmitted diseases2017

Evaluation of Herpes Simplex Virus Type 2 Serological Tests for Use With Dried Blood Spots in Kenya.

Marcia M Hobbs, Sophie W Mwanyumba, Winnie K Luseno, Shane Hartman, Carolyn T Halpern, Denise D Hallfors, Hyunsan Cho

Abstract readEvaluation Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Sexually transmitted diseases, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Marcia M HobbsFrom the *Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC; †National HIV Reference Laboratory, Ministry of Health, Nairobi, Kenya; ‡Pacific Institute for Research and Evaluation; and §Department of Maternal and Child Health, University of North Carolina at Chapel Hill, Chapel Hill, NC.
Sophie W Mwanyumba
Winnie K Luseno
Shane Hartman
Carolyn T Halpern
Denise D Hallfors
Hyunsan Cho

Funding

Virology, Immunology, and Microbiology CoreP30AI050410 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI DAVID M. MARGOLIS · 2001 to 2026
$76.9M
Research Services CoreP2CHD050924 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI KAREN B GUZZO · 2015 to 2026
$9.6M
School Support as Structural HIV Prevention for Adolescent Orphans in Western KenR01MH092215 · NIMH · PACIFIC INSTITUTE FOR RES AND EVALUATION · PI CHO, HYUNSAN · 2011 to 2015
$3.2M
NIAID NIH HHS P30 AI050410NICHD NIH HHS P2C HD050924NIMH NIH HHS R01 MH092215
6 · The paper itself

Abstract

We evaluated 2 assays to detect antibodies to herpes simplex virus type 2 in dried blood spots prepared from blood specimens submitted to a reference laboratory in Kenya. Dried blood spots did not perform well with the Kalon herpes simplex virus type 2 assay. Focus HerpeSelect 2 was 98.8% sensitive and 98.9% specific with dried blood spots.

Indexed as

Antibodies, ViralEnzyme-Linked Immunosorbent AssayHerpes SimplexHerpesvirus 2, HumanHumansReproducibility of ResultsSensitivity and SpecificitySerologic TestsAntibodies, Viral

Identifiers

PMID28081046
PMCPMC5234684

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.