ArticlePhilosophical transactions of the Royal Society of London. Series B, Biological sciences2016
Changes in interoceptive processes following brain stimulation.
Article in Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05684614 (Interoception and Emotion Regulation in Healthy Individuals), which is not on this map. Cited by 53 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Interoception and Emotion Regulation in Healthy Individuals
Who cites it
53 citing papers in PubMed, 2 syntheses or guidelines pooled it, 134 citations in OpenAlex.
- Heartbeat-Evoked Responses in M/EEG: A Systematic Review of Methods With Suggestions for Analysis and Reporting.Psychophysiology · 2026Pooled it
- Pooled it
- MASSAG model: Towards an integrative neuroscience framework linking emotional trauma, pain, and mechanisms of force-based manipulations.Neuroscience and biobehavioral reviews · 2026Review
- Review of methods to derive the heartbeat-evoked potential: past practices and future directions.Social cognitive and affective neuroscience · 2026Review
- Emotional and Social Dimension of Abstract Concepts Meet with Interoception in Right Anterior Insula.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- Comparison of three behavioral cardioception tasks and heartbeat evoked potentials in the same group of healthy volunteers.Scientific reports · 2025Article
- Disentangling interoception and its links to cognitive functioning in fibromyalgia.Scientific reports · 2025Article
- Article
- Interoceptive Dysfunction in Psychiatric Disorders and Non-invasive Neuromodulation for Improving Interoception.Neuroscience bulletin · 2025Review
- The relevance of cardiac and gastric interoception for disordered eating behavior.Journal of eating disorders · 2025Article
- Neurophysiological dynamics of visceral signals in emotion, self and bodily consciousness.Proceedings. Biological sciences · 2025Review
- Neurophysiological dynamics of visceral signals in emotion, self and bodily consciousness.Proceedings. Biological sciences · 2025Review
- Impaired interoception in Colombian victims of armed conflict with PTSD: a preliminary HEP study.Frontiers in psychology · 2025Article
- Exploring the Link Between Interoception and Symptom Severity in Premature Ventricular Contractions.Journal of clinical medicine · 2024Article
- Linking brain-heart interactions to emotional arousal in immersive virtual reality.Psychophysiology · 2024Article
- The Role of Emotion Regulation and Awareness in Psychosocial Stress: An EEG-Psychometric Correlational Study.Healthcare (Basel, Switzerland) · 2024Article
- Attention to cardiac sensations enhances the heartbeat-evoked potential during exhalation.iScience · 2024Article
- Exploring the neural underpinnings of chord prediction uncertainty: an electroencephalography (EEG) study.Scientific reports · 2024Article
- Interoception: Where do we go from here?Quarterly journal of experimental psychology (2006) · 2024Article
- Allostatic-interoceptive anticipation of social rejection.NeuroImage · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The processing and perception of individual internal bodily signals (interoception) has been differentiated to comprise different levels and processes involved. The so-called heartbeat-evoked potential (HEP) offers an additional possibility to examine automatic processing of cardiac signals. Knowledge on neural structures potentially supporting different facets of interoception is still sparse. One way to get insights into neuroanatomical function is to manipulate the activity of different brain structures. In this study, we used repetitive transcranial magnetic stimulation (rTMS) and a continuous theta-burst protocol to inhibit specific central locations of the interoceptive network including the right anterior insula and the right somatosensory cortices and assessed effects on interoceptive facets and the HEP in 18 male participants. Main results were that inhibiting anterior insula resulted in a significant decline in cardiac and respiratory interoceptive accuracy (IAc) and in a consistent decrease in perception confidence. Continuous theta-burst stimulation (cTBS) over somatosensory cortices reduced only cardiac IAc and affected perception confidence. Inhibiting right anterior insula and right somatosensory cortices increased interoceptive sensibility and reduced the HEP amplitude over frontocentral locations. Our findings strongly suggest that cTBS is an effective tool to investigate the neural network supporting interoceptive processes.This article is part of the themed issue 'Interoception beyond homeostasis: affect, cognition and mental health'.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.