ReviewThe Permanente journal2017
Sjögren Syndrome and Pregnancy: A Literature Review.
Review in The Permanente journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 2 syntheses or guidelines pooled it, 60 citations in OpenAlex.
- Pregnancy-Related Attack in Neuromyelitis Optica Spectrum Disorder With AQP4-IgG: A Single-Center Study and Meta-Analysis.Frontiers in immunology · 2021Pooled it
- Sex steroids and autoimmune rheumatic diseases: state of the art.Nature reviews. Rheumatology · 2020Pooled it
- Trophoblast stem cells and syncytiotrophoblasts lack inflammatory responses to LPS but retain robust interferon-mediated antiviral immunity.Reproduction & fertility · 2026Article
- Sjögren's Syndrome With Distal Renal Tubular Acidosis and Hypokalemic Myopathy in Pregnancy: A Rare Case.Clinical case reports · 2025Article
- Efficacy of glucocorticoids treatment in recurrent embryo implantation failure.Cell death discovery · 2025Review
- New-onset seizure In Peripartum period: a case of Sjögren's syndrome with renal artery stenosis.Oxford medical case reports · 2025Article
- The Impact of Menopause on Autoimmune and Rheumatic Diseases.Clinical reviews in allergy & immunology · 2025Review
- Trends in Initial Hospitalizations of Patients with Newly Diagnosed Sjogren's Disease in Poland Between 2012 and 2023: A Retrospective Data Analysis.Journal of clinical medicine · 2025Article
- Exploring the Immunological Aspects and Treatments of Recurrent Pregnancy Loss and Recurrent Implantation Failure.International journal of molecular sciences · 2025Review
- Review
- Fetal and Maternal Outcomes in a Cohort of Patients With Primary Sjogren's Syndrome: An Observational Study.Cureus · 2024Article
- Article
- Epidemiology of Sjögren's: A Systematic Literature Review.Rheumatology and therapy · 2024Review
- Pregnancy and Inflammatory Rheumatological Diseases: A Single-Center Retrospective Cohort Study.Cureus · 2023Article
- A Bio-Social Model during the First 1000 Days Optimizes Healthcare for Children with Developmental Disabilities.Biomedicines · 2022Review
- Article
- Article
- Anaesthetic management for caesarean section in a patient with Sjogren's syndrome.Indian journal of anaesthesia · 2022Article
- Sjögren's syndrome: a systemic autoimmune disease.Clinical and experimental medicine · 2022Review
- Obstetric management of the most common autoimmune diseases: A narrative review.Frontiers in global women's health · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesAutoimmune diseases do not impair fertility, and women with autoimmune diseases who become pregnant are likely to experience more complicated pregnancies than are women without the disease. Pregnancies complicated by these disorders have a high clinical impact on both the pregnancy and the disease. The effect of autoimmune disease on pregnancy differs according to the type of maternal disease, disease activity, severity of organ damage, antibody profile, and drug treatment. Sjögren syndrome is an autoimmune disease with a high prevalence of anti-SS-A (anti-Ro) and anti-SS-B (anti-La) antibodies. Anti-SS-A antibodies are associated with congenital heart block. Data on pregnancy outcomes in primary Sjögren syndrome are scarce.
methodsWe performed a review of the literature regarding pregnancy outcomes in women with Sjögren syndrome.
resultsWomen with Sjögren syndrome are likely to experience more complications during pregnancy than women without an autoimmune disease. Studies show a high incidence of poor fetal outcomes for these patients.
conclusionWomen with Sjögren syndrome require prenatal counseling explaining the risks involved and the need to control the disease well before conception. High-risk pregnancies can be optimally managed by a multidisciplinary team.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.