Evidence map›Paper›PMID 28079866›Full record

SynthesisJournal of perinatology : official journal of the California Perinatal Association2017

Outcomes of twin pregnancies complicated by gestational diabetes: a meta-analysis of observational studies.

R T McGrath, S L Hocking, E S Scott, S K Seeho, G R Fulcher, S J Glastras

Abstract readMeta-Analysis
PubMed Publisher
In one paragraph

Synthesis in Journal of perinatology : official journal of the California Perinatal Association, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 2 pooled it
3.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 2 syntheses or guidelines pooled it, 54 citations in OpenAlex.

  1. Pooled it
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  7. Management of twin pregnancies: Remaining challenges and unanswered questions.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2025
    Review
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  19. Perinatal outcomes in twin pregnancies complicated by gestational diabetes.American journal of obstetrics & gynecology MFM · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

R T McGrathDepartment of Diabetes, Endocrinology and Metabolism, Royal North Shore Hospital, Sydney, NSW 2065, Australia.
S L HockingDepartment of Diabetes, Endocrinology and Metabolism, Royal North Shore Hospital, Sydney, NSW 2065, Australia.
E S ScottDepartment of Diabetes, Endocrinology and Metabolism, Royal North Shore Hospital, Sydney, NSW 2065, Australia.
S K SeehoUniversity of Sydney, Northern Clinical School, Royal North Shore Hospital, Sydney, NSW 2065, Australia.
G R FulcherDepartment of Diabetes, Endocrinology and Metabolism, Royal North Shore Hospital, Sydney, NSW 2065, Australia.
S J GlastrasDepartment of Diabetes, Endocrinology and Metabolism, Royal North Shore Hospital, Sydney, NSW 2065, Australia.
Royal North Shore Hospital · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveGestational diabetes mellitus (GDM) in singleton pregnancy is associated with large for gestational age neonates and adverse perinatal outcomes; however, the impact of GDM in twin pregnancy is unclear. Thus, the aim of this study is to assess the perinatal outcomes of twin pregnancies complicated by GDM by performing a meta-analysis of observational studies. STUDY

designStudies investigating GDM in twin pregnancy were identified through an online search of three databases: Medline, Embase and Web of Science. Selection criteria comprised full paper observational studies (retrospective or prospective) published in English that examined GDM in twin pregnancy compared with non-GDM twin pregnancy and reported on birth weight and/or adverse perinatal outcomes. Random-effects models with inverse-variance weighting were used to calculate standardized mean differences and unadjusted odds ratios. Sensitivity analyses were carried out to determine the impact of possible maternal confounders (body mass index and age) and GDM diagnostic criteria on perinatal outcomes.

resultsThirteen observational studies were included. GDM twins were born at the same gestation as non-GDM twins, with marginally lower birth weight. There was no difference in the incidence of large or small for gestational age neonates. Although there was no correlation between GDM in twin pregnancy and respiratory distress, neonatal hypoglycemic or low Apgar score, GDM twins had a higher rate of neonatal intensive care unit admission (OR 1.49; 95% confidence interval: 1.10, 2.02; P<0.01).

conclusionIdentification and subsequent treatment of GDM in twin pregnancy demonstrates a similar risk of adverse perinatal outcomes compared with non-GDM twin pregnancies.

Indexed as

Pregnancy, TwinAdultBirth WeightDiabetes, GestationalFemaleGestational AgeHumansIncidenceInfant, NewbornObservational Studies as TopicOdds RatioPregnancyPregnancy Outcome

Identifiers

PMID28079866
OpenAlexW2574047274

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.