Evidence map›Paper›PMID 28079619›Full record

ReviewInflammatory bowel diseases2017

The Importance and Challenges of Dietary Intervention Trials for Inflammatory Bowel Disease.

James D Lewis, Lindsey Albenberg, Dale Lee, Mario Kratz, Klaus Gottlieb, Walter Reinisch

Open access · bronzeAbstract readReview
In one paragraph

Review in Inflammatory bowel diseases, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
4.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 44 citations in OpenAlex.

  1. Pooled it
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  18. The Role of Diet in Inflammatory Bowel Disease.Current gastroenterology reports · 2017
    Review
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

James D Lewis*Division of Gastroenterology, Center for Clinical Epidemiology and Biostatistics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania; †Division of Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics, The Children's Hospital of Philadelphia, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania; ‡Division of Gastroenterology, Hepatology, and Nutrition, Seattle Children's Hospital, University of Washington, Seattle, Washington; §Public Health Sciences Division, Departments of Epidemiology and Medicine, Fred Hutchinson Cancer Research Center, University of Washington, Seattle, Washington; ‖George Washington University, Washington, DC; ¶Division of Gastroenterology and Hepatology, McMaster University, Hamilton, Ontario, Canada; and **Division of Gastroenterology and Hepatology, Medical University of Vienna, Vienna, Austria.
Lindsey Albenberg
Dale Lee
Mario Kratz
Klaus Gottlieb
Walter Reinisch
University of Pennsylvania · USUniversity of Washington · USGeorge Washington University · USMcMaster University · CA

Funding

Test-Treat strategy to prevent ulcerative colitis relapseK24DK078228 · NIDDK · UNIVERSITY OF PENNSYLVANIA · PI LEWIS, JAMES D · 2007 to 2016
$1.9M
NIDDK NIH HHS K24 DK078228
6 · The paper itself

Abstract

Inflammatory bowel disease is believed to be caused by a combination of genetic and environmental stimuli such as our diet. Diets high in meat and fats and low in fruits and vegetables have been associated with new-onset inflammatory bowel disease. This has triggered interest in using dietary modification as a treatment. The 3 principle models of dietary intervention are supplementation with selected dietary components, exclusion of selected dietary components, or use of dietary formulas in place of a normal diet. Despite the high level of interest in dietary interventions as a treatment for inflammatory bowel disease, few well-designed clinical trials have been conducted to firmly establish the optimal diet to induce or maintain remission. This may be in part related to the challenges of conducting dietary intervention trials. This review examines these challenges and potential approaches to be used in dietary intervention trials.

Indexed as

Clinical Trials as TopicDietDietary SupplementsFood, FormulatedHumansInflammatory Bowel DiseasesResearch Design

Identifiers

PMID28079619
PMCPMC5250567
OpenAlexW2579224340

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.