Evidence map›Paper›PMID 28079292›Full record

ReviewMolecular reproduction and development2017

Germ cell tumors: Insights from the Drosophila ovary and the mouse testis.

Helen K Salz, Emily P Dawson, Jason D Heaney

Open access · bronzeAbstract readReview
In one paragraph

Review in Molecular reproduction and development, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. An autoregulatory switch in sex-specificDevelopment (Cambridge, England) · 2020
    Article
  7. Review
  8. Drosophila as a Model for Tumor-Induced Organ Wasting.Advances in experimental medicine and biology · 2019
    Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Helen K SalzDepartment of Genetics and Genome Sciences, Case Western Reserve University, Cleveland, Ohio.ORCID 0000-0003-1120-7464
Emily P DawsonDepartment of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas.
Jason D HeaneyDepartment of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas.
Baylor College of Medicine · USCase Western Reserve University · US

Funding

Sexual identity and germ cell differentiation in the Drosophila ovaryR01GM102141 · NIGMS · CASE WESTERN RESERVE UNIVERSITY · PI SALZ, HELEN KAREN · 2013 to 2016
$1.2M
NIGMS NIH HHS R01 GM102141
6 · The paper itself

Abstract

Ovarian and testicular germ cell tumors of young adults are thought to arise from defects in germ cell development, but the molecular mechanisms underlying malignant transformation are poorly understood. In this review, we focus on the biology of germ cell tumor formation in the Drosophila ovary and the mouse testis, for which evidence supports common underlying mechanisms, such as blocking initiation into the differentiation pathway, impaired lineage progression, and sexual identity instability. We then discuss how these concepts inform our understanding of the disease in humans. Mol. Reprod. Dev. 84: 200-211, 2017. © 2017 Wiley Periodicals, Inc.

Indexed as

Cell DifferentiationAnimalsFemaleMaleMiceNeoplasms, Germ Cell and EmbryonalOvarian NeoplasmsOvaryTesticular NeoplasmsTestis

Identifiers

PMID28079292
PMCPMC5365366
OpenAlexW2578555548

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.