Evidence map›Paper›PMID 28079275›Full record

ReviewAmerican journal of industrial medicine2017

Non-malignant respiratory disease among workers in industries using styrene-A review of the evidence.

Randall J Nett, Jean M Cox-Ganser, Ann F Hubbs, Avima M Ruder, Kristin J Cummings, Yuh-Chin T Huang, Kathleen Kreiss

Open access · greenAbstract readReview
In one paragraph

Review in American journal of industrial medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 41 citations in OpenAlex.

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  13. Occupational Bronchiolitis: An Update.Clinics in chest medicine · 2020
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Randall J NettRespiratory Health Division, Centers for Disease Control and Prevention (CDC), National Institute for Occupational Safety and Health (NIOSH), Morgantown, West Virginia.
Jean M Cox-GanserRespiratory Health Division, Centers for Disease Control and Prevention (CDC), National Institute for Occupational Safety and Health (NIOSH), Morgantown, West Virginia.
Ann F HubbsHealth Effects Laboratory Division, National Institute for Occupational Safety and Health (NIOSH), CDC, Morgantown, West Virginia.
Avima M RuderDivision of Surveillance, Hazard Evaluations, and Field Studies, National Institute for Occupational Safety and Health (NIOSH), CDC, Cincinnati, Ohio.
Kristin J CummingsRespiratory Health Division, Centers for Disease Control and Prevention (CDC), National Institute for Occupational Safety and Health (NIOSH), Morgantown, West Virginia.
Yuh-Chin T HuangDivision of Pulmonary and Critical Care Medicine, Duke University Medical Center, Durham, North Carolina.
Kathleen KreissRespiratory Health Division, Centers for Disease Control and Prevention (CDC), National Institute for Occupational Safety and Health (NIOSH), Morgantown, West Virginia.
National Institute for Occupational Safety and Health · USDuke Medical Center · US

Funding

Intramural CDC HHS CC999999
6 · The paper itself

Abstract

backgroundAsthma and obliterative bronchiolitis (OB) cases have occurred among styrene-exposed workers. We aimed to investigate styrene as a risk factor for non-malignant respiratory disease (NMRD).

methodsFrom a literature review, we identified case reports and assessed cross-sectional and mortality studies for strength of evidence of positive association (i.e., strong, intermediate, suggestive, none) between styrene exposure and NMRD-related morbidity and mortality.

resultsWe analyzed 55 articles and two unpublished case reports. Ten OB cases and eight asthma cases were identified. Six (75%) asthma cases had abnormal styrene inhalation challenges. Thirteen (87%) of 15 cross-sectional studies and 12 (50%) of 24 mortality studies provided at least suggestive evidence that styrene was associated with NMRD-related morbidity or mortality. Six (66%) of nine mortality studies assessing chronic obstructive pulmonary disease-related mortality indicated excess mortality.

conclusionsAvailable evidence suggests styrene exposure is a potential risk factor for NMRD. Additional studies of styrene-exposed workers are warranted. Am. J. Ind. Med. 60:163-180, 2017. © 2016 Wiley Periodicals, Inc.

Indexed as

AsthmaBronchiolitis ObliteransHumansOccupational DiseasesOccupational ExposureRisk FactorsStyreneStyreneasthmabronchiolitis obliteransnon-malignant respiratory diseaseobliterative bronchiolitisoccupational asthmaoccupational lung diseasestyrenestyrolvinylbenzene

Identifiers

PMID28079275
PMCPMC5379121
OpenAlexW2572458264

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.