Evidence map›Paper›PMID 28079108›Full record

ArticleScientific reports2017

Improving the Concentrations of the Active Components in the Herbal Tea Ingredient, Uraria crinita: The Effect of Post-harvest Oven-drying Processing.

Jung Chao, Yuntao Dai, Hao-Yuan Cheng, Wing Lam, Yung-Chi Cheng, Ke Li, Wen-Huang Peng, Li-Heng Pao, Ming-Tsuen Hsieh, Xue-Mei Qin and 1 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.6field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 36 citations in OpenAlex.

  1. Article
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  9. African Nightshade (Nutrients · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 3 countries.

Jung ChaoInstitute of Pharmacology, National Yang-Ming University, College of Medicine, Taipei, Taiwan.
Yuntao DaiInstitute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, China.
Hao-Yuan ChengDepartment of Nursing, Chung-Jen Junior College of Nursing, Health Sciences and Management, Chia-Yi, Taiwan.
Wing LamDepartment of Pharmacology, Yale University School of Medicine, New Haven, Connecticut, United States.
Yung-Chi ChengDepartment of Pharmacology, Yale University School of Medicine, New Haven, Connecticut, United States.
Ke LiModern Research Center for Traditional Chinese Medicine of Shanxi University, Shanxi, China.
Wen-Huang PengDepartment of Chinese Pharmaceutical Sciences and Chinese Medicine Resources, China Medical University, Taiwan.
Li-Heng PaoResearch Center for Industry of Human Ecology, Graduate Institute of Health-Industry Technology and Department of Nutrition and Health Sciences, Chang Gung University of Science and Technology, Kweishan, Taoyuan, Taiwan.
Ming-Tsuen HsiehDepartment of Chinese Pharmaceutical Sciences and Chinese Medicine Resources, China Medical University, Taiwan.
Xue-Mei QinModern Research Center for Traditional Chinese Medicine of Shanxi University, Shanxi, China.
Meng-Shiou LeeDepartment of Chinese Pharmaceutical Sciences and Chinese Medicine Resources, China Medical University, Taiwan.
China Medical University · TWShanxi University of Traditional Chinese Medicine · CNYale University · USChinese Academy of Medical Sciences & Peking Union Medical College · CNNational Defense Medical Center · TWNational Yang Ming Chiao Tung University · TW

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Clinical Study of PHY906, a Novel Chinese Herbal Medicine, as a Modulator of IrinP01CA154295 · NCI · YALE UNIVERSITY · PI CHENG, YUNG-CHI · 2011 to 2016
$6.4M
NCATS NIH HHS UL1 TR001863NCI NIH HHS P01 CA154295
6 · The paper itself

Abstract

Uraria crinita is widely used as a popular folk drink; however, little is known about how the post-harvest operations affect the chemical composition and bioactivity of UC. We assessed three drying methods (Oven-drying, Air-drying, Sun-drying), as well as the Oven-drying temperature using metabolomics approaches and bioactivity assays. The samples processed at 40 degree show a greater effect on the levels of estrogen receptor-alpha activity and nuclear factor erythroid 2-related factor 2 activity, anti-oxidative activity, and cyclooxygenase-2 inhibition compared with the other samples. A multivariate analysis showed a clear separation between the 40 degree Oven-dried samples and the other samples, which is consistent with the results of bioactivity assay. These results are ascribed to at least two-fold increase in the concentrations of flavonoids, spatholosineside A and triterpenoids in the oven-dried samples compared with the other groups. The proposed Oven-drying method at 40 degree results in an improved quality of UC.

Indexed as

Teas, HerbalDesiccationDrug CompoundingFabaceaeFlavonoidsGlycosidesPhytochemicalsPlant StructuresTemperatureTerpenesFlavonoidsGlycosidesPhytochemicalsspatholosineside ATeas, HerbalTerpenes

Identifiers

PMID28079108
PMCPMC5227699
OpenAlexW2574468372

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.