ArticleClinical and translational science2017
Microphysiological Systems ("Organs-on-Chips") for Drug Efficacy and Toxicity Testing.
Article in Clinical and translational science, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed.
- Versatile Microfluidic System for Creating Recirculating Unidirectional Flow for On-Chip Cultures of Barrier Tissues.Bioengineering (Basel, Switzerland) · 2026Article
- Regulatory integration of new approach methodologies for human-relevant developmental and reproductive toxicity (DART) assessment: A systematic cross-sector review.Toxicology reports · 2026Review
- Organoids, organ-on-a-chip, and microtumors: Biomimetic 3D tumor models advancing drug development and precision medicine.Acta pharmaceutica Sinica. B · 2026Review
- Organoids in drug development: from predictive models to regulatory integration.Drug discovery today · 2026Review
- Optimization of Application-Driven Development ofTissue engineering. Part B, Reviews · 2022Review
- Characterizing the reproducibility in using a liver microphysiological system for assaying drug toxicity, metabolism, and accumulation.Clinical and translational science · 2021Article
- A Synthetic Hydrogel, VitroGelFrontiers in pharmacology · 2021Article
- Microphysiological systems for the modeling of wound healing and evaluation of pro-healing therapies.Journal of materials chemistry. B · 2020Review
- Applications of the microphysiology systems database for experimental ADME-Tox and disease models.Lab on a chip · 2020Article
- Article
- A human-on-a-chip approach to tackling rare diseases.Drug discovery today · 2019Review
- Liver Microphysiological Systems for Predicting and Evaluating Drug Effects.Clinical pharmacology and therapeutics · 2019Review
- Kidneys on Chips: Emerging Technology for Preclinical Drug Development.Clinical journal of the American Society of Nephrology : CJASN · 2019Article
- Advancing internal exposure and physiologically-based toxicokinetic modeling for 21st-century risk assessments.Journal of exposure science & environmental epidemiology · 2019Review
- Assessment of Drug-Induced Toxicity Biomarkers in the Brain Microphysiological System (MPS) Using Targeted and Untargeted Molecular Profiling.Frontiers in big data · 2019Article
- Maximizing the impact of microphysiological systems with in vitro-in vivo translation.Lab on a chip · 2018Article
- Use of porous membranes in tissue barrier and co-culture models.Lab on a chip · 2018Review
- Bioengineered humanized livers as better three-dimensional drug testing model system.World journal of hepatology · 2018Article
- Mining the Potential of Label-Free Biosensors for In Vitro Antipsychotic Drug Screening.Biosensors · 2018Article
- The US Federal Tox21 Program: A strategic and operational plan for continued leadership.ALTEX · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
PubMed holds no abstract for this paper.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.