Evidence map›Paper›PMID 28078641›Full record

ArticleObesity surgery2017

Staple Line Leak After Primary Sleeve Gastrectomy-Risk Factors and Mid-term Results: Do Patients Still Benefit from the Weight Loss Procedure?

Frank Benedix, Oliver Poranzke, Daniele Adolf, Stephanie Wolff, Hans Lippert, Jörg Arend, Thomas Manger, Christine Stroh, Obesity Surgery Working Group Competence Network Obesity

Registry-linked trialAbstract read
PubMed Publisher
In one paragraph

Article in Obesity surgery, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04834323 (Short Term Outcome Of Distal Mesogastric Fixation After Laparoscopic Sleeve Gastrectomy; A Randomized Control Trial), which is not on this map. Cited by 31 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 1 pooled it
4.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04834323 nacompletednot on this mapstarted 2019, after this paper: background citation

Short Term Outcome Of Distal Mesogastric Fixation After Laparoscopic Sleeve Gastrectomy; A Randomized Control Trial

TypeinterventionalSponsorZagazig UniversityRan2019 to 2021Enrolled84ConditionsBariatric Surgery CandidateArmsdistal mesogastric fixation after sleeve gastrectomy
3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 1 synthesis or guideline pooled it, 50 citations in OpenAlex.

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  15. LAPAROSCOPIC BARIATRIC SURGERY IN ADOLESCENTS: EARLY AND FIVE- YEAR CLINICAL AND LABORATORY ASSESSMENT.Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery · 2023
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  18. THE ROUTINE USE OF THE METHYLENE BLUE TEST IN SLEEVE GASTRECTOMY: WHY NOT?Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Frank BenedixDepartment of Surgery, University Hospital Magdeburg, Leipziger Strasse 44, D-39120, Magdeburg, Germany. frankbenedix@gmx.de.
Oliver PoranzkeDepartment of Surgery, University Hospital Magdeburg, Leipziger Strasse 44, D-39120, Magdeburg, Germany.
Daniele AdolfStatConsult Magdeburg, Halberstädter Strasse 40a, D-39112, Magdeburg, Germany.
Stephanie WolffDepartment of Surgery, University Hospital Magdeburg, Leipziger Strasse 44, D-39120, Magdeburg, Germany.
Hans LippertDepartment of Surgery, University Hospital Magdeburg, Leipziger Strasse 44, D-39120, Magdeburg, Germany.
Jörg ArendDepartment of Surgery, University Hospital Magdeburg, Leipziger Strasse 44, D-39120, Magdeburg, Germany.
Thomas MangerSRH Municipal Hospital Gera, Straße des Friedens 122, D-07548, Gera, Germany.
Christine StrohSRH Municipal Hospital Gera, Straße des Friedens 122, D-07548, Gera, Germany.
Obesity Surgery Working Group Competence Network Obesity
University Hospital Magdeburg · DESRH Wald-Klinikum Gera · DEInfoConsult (Germany) · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundStaple line leak after laparoscopic sleeve gastrectomy (LSG) still represents the most feared complication. The purpose of this study was to investigate whether there are factors that increase the risk for a leakage. Furthermore, we aimed to analyze the impact of a leak on weight change and resolution of comorbidities.

methodsSince 2005, data from obese patients that undergo bariatric procedures in Germany are prospectively registered. For the current analysis, all adult subjects that had undergone primary LSG from 2005 to 2014 were considered.

resultsOverall, 241/15,756 (1.53%) patients experienced a leak. The occurrence of a leakage resulted in a significant increase of the mortality rate (3.7 vs. 0.2%; p < 0.01). Percent excess weight loss did not differ between leak and non-leak patients, both, at 12 (64.2 vs. 60.9%; p = 1.0) and 24 months (68.5 vs. 64.0%, p = 0.86). Similarly, no significant difference was observed for resolution rate of all comorbid conditions. Matched pair analysis confirmed these findings. Multivariable analysis identified operation time, conversion, intraoperative complications, and hypertension and degenerative joint disease as risk factors for a leak. Oversewing the staple line was associated with the lowest risk.

conclusionThe postoperative staple line leak after primary LSG significantly increases postoperative morbidity and mortality. We found that there are patient-related factors and operative variables that predispose to leakage after LSG. However, the occurrence of a leakage does not adversely impact the weight loss and resolution of comorbidities in the mid-term.

Indexed as

GastrectomyObesity, MorbidSurgical StaplingGermanyHumansPostoperative ComplicationsProspective StudiesRisk FactorsGerman multicenter trialLeakageOutcomeRisk factorsSleeve gastrectomy

Identifiers

PMID28078641
OpenAlexW2572577847

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.