Evidence map›Paper›PMID 28078447›Full record

ArticleClinical research in cardiology : official journal of the German Cardiac Society2017

Trends in aortic valve replacement in Germany in 2015: transcatheter versus isolated surgical aortic valve repair.

Luise Gaede, Johannes Blumenstein, Won-Keun Kim, Christoph Liebetrau, Oliver Dörr, Holger Nef, Christian Hamm, Albrecht Elsässer, Helge Möllmann

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in Clinical research in cardiology : official journal of the German Cardiac Society, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 1 pooled it
7.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 1 synthesis or guideline pooled it, 56 citations in OpenAlex.

  1. Transcatheter aortic valve replacement for pure aortic valve regurgitation: "on-label" versus "off-label" use of TAVR devices.Clinical research in cardiology : official journal of the German Cardiac Society · 2019
    Pooled it
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Observational
  9. Early and late risk of ischemic stroke after TAVR as compared to a nationwide background population.Clinical research in cardiology : official journal of the German Cardiac Society · 2020
    Article
  10. Review
  11. Lower mortality in an all-comers aortic stenosis population treated with TAVI in comparison to SAVR.Clinical research in cardiology : official journal of the German Cardiac Society · 2020
    Article
  12. Article
  13. Transvascular transcatheter aortic valve implantation in 2017.Clinical research in cardiology : official journal of the German Cardiac Society · 2020
    Article
  14. Article
  15. Observational
  16. Incidence and impact of prosthesis-patient mismatch following transcatheter aortic valve implantation.Clinical research in cardiology : official journal of the German Cardiac Society · 2019
    Article
  17. Prophylactic ECMO during TAVI in patients with depressed left ventricular ejection fraction.Clinical research in cardiology : official journal of the German Cardiac Society · 2019
    Observational
  18. Article
  19. Observational
  20. Heart Valve Disease Awareness Survey 2017: what did we achieve since 2015?Clinical research in cardiology : official journal of the German Cardiac Society · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Luise GaedeDepartment of Internal Medicine, St. Johannes-Hospital, Johannesstrasse 9-13, 44137, Dortmund, Germany.
Johannes BlumensteinDepartment of Internal Medicine, St. Johannes-Hospital, Johannesstrasse 9-13, 44137, Dortmund, Germany.
Won-Keun KimDepartment of Cardiology, Kerckhoff Heart and Thorax Center, Bad Nauheim, Germany.
Christoph LiebetrauDepartment of Cardiology, Kerckhoff Heart and Thorax Center, Bad Nauheim, Germany.
Oliver DörrDepartment of Cardiology and Angiology, Medical Clinic I, University of Giessen, Giessen, Germany.
Holger NefDepartment of Cardiology and Angiology, Medical Clinic I, University of Giessen, Giessen, Germany.
Christian HammDepartment of Cardiology, Kerckhoff Heart and Thorax Center, Bad Nauheim, Germany.
Albrecht ElsässerDepartment of Cardiology, Klinikum Oldenburg, Oldenburg, Germany.
Helge MöllmannDepartment of Internal Medicine, St. Johannes-Hospital, Johannesstrasse 9-13, 44137, Dortmund, Germany. moellmann@me.com.
St.-Johannes-Hospital Dortmund · DEKerckhoff Klinik · DEUniversity of Giessen · DEKlinikum Oldenburg · DEUniversitätsklinikum Gießen und Marburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsWe analysed the number of procedures, indications, and in-hospital mortality rates of all patients undergoing isolated surgical aortic valve replacement (sAVR) or transvascular (TV-) and transapical (TA-) transcatheter aortic valve implantation (TAVI) from 2012 to 2015 in Germany. METHODS AND

resultsMore than 31,000 aortic valve procedures were performed in 2015 in Germany, representing a total increase of 4.5% over 2014. TV-TAVI accounts for 13,108 of these procedures, with an increase of 21%, whereas the numbers of isolated sAVR and TA-TAVI decreased slightly. Age, frailty, high risk, and patients' choice were the main reasons for a catheter-based intervention. In 2015, the in-hospital mortality rate after TV-TAVI decreased to 3.4%, approaching that of sAVR (2.9%), despite a considerably higher baseline risk. A stratified analysis according to the German aortic valve (AKL) score demonstrated a further decrease of the in-hospital mortality for TV-TAVI, showing a lower in-hospital mortality rate than expected in all risk groups. Importantly, this also accounts for the lowest risk group with an AKL score <3% showing an in-hospital mortality rate of 1.7%, which is now comparable to that of sAVR (1.5%). In all other risk groups, the in-hospital mortality in patients undergoing TV-TAVI was lower than in patients undergoing sAVR.

conclusionsMortality after TV-TAVI keeps decreasing over the last years and equals that of SAVR in the lowest risk cohort in the meanwhile. All TV-TAVI patients have significantly lower observed than expected mortality, which will further lead to a redefinition of standard of care.

Indexed as

AgedAged, 80 and overAge FactorsAortic ValveCohort StudiesGermanyHeart Valve ProsthesisHeart Valve Prosthesis ImplantationHospital MortalityHumansMiddle AgedTranscatheter Aortic Valve ReplacementTreatment OutcomeAKL scoreAortic valve replacementLogistic EuroScoreMortalityOutcomeTAVI

Identifiers

PMID28078447
OpenAlexW2575427326

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.