Evidence map›Paper›PMID 28078302›Full record

ReviewBioMed research international2016

The Evolution of Human Basophil Biology from Neglect towards Understanding of Their Immune Functions.

Markus Steiner, Sara Huber, Andrea Harrer, Martin Himly

Abstract readReview
In one paragraph

Review in BioMed research international, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Mast Cells and Basophils in IgE-Independent Anaphylaxis.International journal of molecular sciences · 2023
    Review
  5. Article
  6. Review
  7. Article
  8. Basophil Activation Test: Old and New Applications in Allergy.Current allergy and asthma reports · 2018
    Review
  9. Review
  10. Cattle TickFrontiers in cellular and infection microbiology · 2017
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Markus SteinerDivision of Allergy & Immunology, Department of Molecular Biology, University of Salzburg, Salzburg, Austria; Laboratory for Immunological & Molecular Cancer Research, Paracelsus Medical University, Salzburg, Austria.
Sara HuberDivision of Allergy & Immunology, Department of Molecular Biology, University of Salzburg, Salzburg, Austria.
Andrea HarrerDivision of Allergy & Immunology, Department of Molecular Biology, University of Salzburg, Salzburg, Austria; Department of Neurology, Paracelsus Medical University, Salzburg, Austria.
Martin HimlyDivision of Allergy & Immunology, Department of Molecular Biology, University of Salzburg, Salzburg, Austria.ORCID 0000-0001-5416-085X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Being discovered long ago basophils have been neglected for more than a century. During the past decade evidence emerged that basophils share features of innate and adaptive immunity. Nowadays, basophils are best known for their striking effector role in the allergic reaction. They hence have been used for establishing new diagnostic tests and therapeutic approaches and for characterizing natural and recombinant allergens as well as hypoallergens, which display lower or diminished IgE-binding activity. However, it was a long way from discovery in 1879 until identification of their function in hypersensitivity reactions, including adverse drug reactions. Starting with a historical background, this review highlights the modern view on basophil biology.

Indexed as

Adaptive ImmunityImmunity, InnateAllergensBasophilsHumansHypersensitivityImmunoglobulin EAllergensImmunoglobulin E

Identifiers

PMID28078302
PMCPMC5204076

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.