Evidence map›Paper›PMID 28078149›Full record

ArticleCase reports in infectious diseases2016

Rapid Fatal Outcome of Cryptococcal Meningoencephalitis in a Non-HIV Immunocompromised Patient with a Low Fluconazole Susceptibility Isolate: A Case Report from Madagascar.

Mihaja Raberahona, Rivonirina A Rakotoarivelo, Njary Randriamampionona, Angelot F Rakotomalala, Tiana Razafinambinintsoa, Thomas Bénet, Philippe Vanhems, Mamy J D D Randria, Muriel Cornet, Mala Rakoto-Andrianarivelo

Open access · goldAbstract readCase Reports
In one paragraph

Article in Case reports in infectious diseases, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Mihaja RaberahonaService des Maladies Infectieuses, HU Joseph Raseta de Befelatanana, Antananarivo, Madagascar.ORCID 0000-0001-8857-5834
Rivonirina A RakotoariveloService des Maladies Infectieuses, CHU Tambohobe, Fianarantsoa, Madagascar.
Njary RandriamampiononaCentre d'Infectiologie Charles Mérieux, Antananarivo, Madagascar.
Angelot F RakotomalalaCentre d'Infectiologie Charles Mérieux, Antananarivo, Madagascar.
Tiana RazafinambinintsoaService des Maladies Infectieuses, HU Joseph Raseta de Befelatanana, Antananarivo, Madagascar.
Thomas BénetService d'Hygiène, Epidémiologie et Prévention, Hospices Civils de Lyon, Lyon, France; Laboratoire des Pathogènes Emergents, Fondation Mérieux, Centre International de Recherche en Infectiologie (CIRI), INSERM U1111, CNRS UMR5308, ENS de Lyon, UCBL1, Lyon, France.
Philippe VanhemsService d'Hygiène, Epidémiologie et Prévention, Hospices Civils de Lyon, Lyon, France; Laboratoire des Pathogènes Emergents, Fondation Mérieux, Centre International de Recherche en Infectiologie (CIRI), INSERM U1111, CNRS UMR5308, ENS de Lyon, UCBL1, Lyon, France.
Mamy J D D RandriaService des Maladies Infectieuses, HU Joseph Raseta de Befelatanana, Antananarivo, Madagascar.
Muriel CornetLaboratoire de Parasitologie-Mycologie, Institut de Biologie et de Pathologie, CHU Grenoble Alpes, Grenoble, France; Laboratoire TIMC-IMAG-TheREx, Université Grenoble-Alpes, Grenoble, France.
Mala Rakoto-AndrianariveloCentre d'Infectiologie Charles Mérieux, Antananarivo, Madagascar.ORCID 0000-0001-6767-9554
University of Antananarivo · MGUniversité Claude Bernard Lyon 1 · FRCentre Hospitalier Universitaire de Grenoble · FRUniversité de Fianarantsoa · MG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cryptococcal meningoencephalitis is considered rare in HIV-negative individuals. In Madagascar, the epidemiology of cryptococcosis has not yet been well described, neither in immunocompetent nor in immunocompromised patients. We report here the first Malagasy detailed case of cryptococcal meningoencephalitis in a non-HIV immunocompromised adult patient carrying a low fluconazole susceptibility isolate. We emphasize the importance of early and accurate diagnosis to meet the challenges of managing cryptococcosis in developing countries.

Identifiers

PMID28078149
PMCPMC5203877
OpenAlexW2562923706

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.