ReviewNeural plasticity2016
Progress of Research on Diffuse Axonal Injury after Traumatic Brain Injury.
Review in Neural plasticity, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
37 citing papers in PubMed, 97 citations in OpenAlex.
- The Impact of Cognitive Behavioral Therapy for Insomnia on Neurofilament Light and Phosphorylated Tau in Individuals with a Concussion.Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists · 2025Trial
- Time-Dependent Diagnostic Windows After Isolated Diffuse Axonal Brain Injury in Rats.Diagnostics (Basel, Switzerland) · 2026Article
- A case report on delayed: onset diffuse axonal injury.Annals of medicine and surgery (2012) · 2025Article
- Incidence and mortality related risk factors in patients with severe traumatic brain injury: A meta‑analysis.Experimental and therapeutic medicine · 2025Article
- Dynamic changes in neuron-specific enolase level to glasgow coma scale score ratio predict long-term neurological function of diffuse axonal injury patients.BMC neurology · 2025Observational
- Diffusion Tensor Imaging as Neurologic Predictor in Patients Affected by Traumatic Brain Injury: Scoping Review.Brain sciences · 2025Review
- Metabolic pathway dysregulation in diffuse axonal injury: a multimodal biomarker approach for early diagnosis and mechanistic insights.Frontiers in neurology · 2025Article
- Traumatic Axonal Injury Successfully Treated with Secretome Followed by Mesenchymal Stem Cells Therapy.European journal of case reports in internal medicine · 2025Article
- Development of a time-resolved immunochromatographic test strip for rapid and quantitative determination of GFAP in serum.Mikrochimica acta · 2024Article
- Reduced influence of perceptual context in mild traumatic brain injury is not an illusion.Scientific reports · 2024Article
- Traumatic brain injuries: a neuropsychological review.Frontiers in behavioral neuroscience · 2024Review
- The effect ofSurgical neurology international · 2024Article
- Role of integrin and its potential as a novel postmortem biomarker in traumatic axonal injury.International journal of legal medicine · 2023Article
- Traumatic Brain Injury Induces Microglial and Caspase3 Activation in the Retina.International journal of molecular sciences · 2023Article
- Review
- A bibliometric analysis on traumatic brain injury in forensic medicine of a half-century (1972-2021).Frontiers in neurology · 2023Article
- Association of Traumatic Brain Injury with Late Life Neuropathological Outcomes in a Community-Based Cohort.Journal of Alzheimer's disease : JAD · 2023Article
- Assessing Cognitive Behavioral Therapy for Insomnia to Improve Sleep Outcomes in Individuals With a Concussion: Protocol for a Delayed Randomized Controlled Trial.JMIR research protocols · 2022Article
- UPLC/Q-TOF MS-Based Urine Metabonomics Study to Identify Diffuse Axonal Injury Biomarkers in Rat.Disease markers · 2022Article
- The Outcome of Neurorehabilitation Efficacy and Management of Traumatic Brain Injury.Frontiers in human neuroscience · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The current work reviews the concept, pathological mechanism, and process of diagnosing of DAI. The pathological mechanism underlying DAI is complicated, including axonal breakage caused by axonal retraction balls, discontinued protein transport along the axonal axis, calcium influx, and calpain-mediated hydrolysis of structural protein, degradation of axonal cytoskeleton network, the changes of transport proteins such as amyloid precursor protein, and changes of glia cells. Based on the above pathological mechanism, the diagnosis of DAI is usually made using methods such as CT, traditional and new MRI, biochemical markers, and neuropsychological assessment. This review provides a basis in literature for further investigation and discusses the pathological mechanism. It may also facilitate improvement of the accuracy of diagnosis for DAI, which may come to play a critical role in breaking through the bottleneck of the clinical treatment of DAI and improving the survival and quality of life of patients through clear understanding of pathological mechanisms and accurate diagnosis.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.