Evidence map›Paper›PMID 28078083›Full record

ArticleJournal of animal science and biotechnology2017

Over-expression of Toll-like receptor 2 up-regulates heme oxygenase-1 expression and decreases oxidative injury in dairy goats.

Shoulong Deng, Kun Yu, Wuqi Jiang, Yan Li, Shuotian Wang, Zhuo Deng, Yuchang Yao, Baolu Zhang, Guoshi Liu, Yixun Liu and 1 more

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Journal of animal science and biotechnology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 38 citations in OpenAlex.

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  7. Cells · 2021
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 2 countries.

Shoulong Deng *State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, 100101 China.
Kun Yu *Laboratory of Animal Genetics and Breeding, College of Animal Science and Technology, China Agricultural University, Beijing, 100193 People's Republic of China.
Wuqi JiangLaboratory of Animal Genetics and Breeding, College of Animal Science and Technology, China Agricultural University, Beijing, 100193 People's Republic of China.
Yan LiLaboratory of Animal Genetics and Breeding, College of Animal Science and Technology, China Agricultural University, Beijing, 100193 People's Republic of China.
Shuotian WangLaboratory of Animal Genetics and Breeding, College of Animal Science and Technology, China Agricultural University, Beijing, 100193 People's Republic of China.
Zhuo DengDepartment of Animal Science, Oklahoma State University, Stillwater, OK 74078 USA.
Yuchang YaoCollege of Animal Science and Technology, Northeast Agricultural University, Harbin, 150030 People's Republic of China.
Baolu ZhangState Oceanic Administration, Beijing, 100860 People's Republic of China.
Guoshi LiuLaboratory of Animal Genetics and Breeding, College of Animal Science and Technology, China Agricultural University, Beijing, 100193 People's Republic of China.
Yixun LiuState Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, 100101 China.
Zhengxing LianLaboratory of Animal Genetics and Breeding, College of Animal Science and Technology, China Agricultural University, Beijing, 100193 People's Republic of China.ORCID 0000-0002-2060-0324
Beijing University of Agriculture · CNChinese Academy of Sciences · CNNortheast Agricultural University · CNOklahoma State University · USState Council of the People's Republic of China · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMastitis, an infection caused by Gram-positive bacteria, produces udder inflammation and oxidative injury in milk-producing mammals. Toll-like receptor 2 (TLR2) is important for host recognition of invading Gram-positive microbes. Over-expression of

methodsWe over-expressed

resultsCompared with wild-type controls, measurements of various oxidative stress-related molecules showed that

conclusionsThe results indicate that the oxidative injury in goats over-expressing

Indexed as

Haem oxygenaseNrf2 signal pathwayToll-like receptor 2Transgenic goats

Identifiers

PMID28078083
PMCPMC5223356
OpenAlexW2569553046

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.