Evidence map›Paper›PMID 28078070›Full record

ArticleEuropean journal of translational myology2016

Stem Cells and Tissue Niche: Two Faces of the Same Coin of Muscle Regeneration.

Bianca Maria Scicchitano, Gigliola Sica, Antonio Musarò

Abstract read
In one paragraph

Article in European journal of translational myology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Nutrition and microRNAs: Novel Insights to Fight Sarcopenia.Antioxidants (Basel, Switzerland) · 2020
    Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Review
  12. Review
  13. 2019Spring PaduaMuscleDays: Translational Myology and Mobility Medicine.European journal of translational myology · 2019
    Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Bianca Maria ScicchitanoInstitute of Histology and Embryology, Catholic University School of Medicine , Rome, Italy.
Gigliola SicaInstitute of Histology and Embryology, Catholic University School of Medicine , Rome, Italy.
Antonio MusaròInstitute Pasteur Cenci-Bolognetti; DAHFMO-Unit of Histology and Medical Embryology, IIM; Sapienza University of Rome, Italy; Center for Life Nano Science@Sapienza, Istituto Italiano di Tecnologia, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Capacity of adult muscle to regenerate in response to injury stimuli represents an important homeostatic process. Regeneration is a highly coordinated program that partially recapitulates the embryonic developmental program. However, muscle regeneration is severely compromised in several pathological conditions. It is likely that the restricted tissue repair program under pathological conditions is due to either progressive loss of stem cell populations or to missing signals that limit the damaged tissues to efficiently activate a regenerative program. It is therefore plausible that loss of control over these cell fates might lead to a pathological cell transdifferentiation, limiting the ability of a pathological muscle to sustain an efficient regenerative process. The critical role of microenvironment on stem cells activity and muscle regeneration is discussed.

Indexed as

IGF-1muscle pathologiesmuscle regenerationsatellite cellstissue niche

Identifiers

PMID28078070
PMCPMC5220217

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.