Evidence map›Paper›PMID 28078041›Full record

ArticleAmerican journal of translational research2016

Treatment of de-peritonealized intestine with 4DryField

Markus Winny, Lavinia Maegel, Leonie Victoria Grethe, Danny Jonigk, Paul Borchert, Alexander Kaltenborn, Harald Schrem, Juergen Klempnauer, Daniel Poehnert

Open access · greenAbstract read
In one paragraph

Article in American journal of translational research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Effect of 4DryFieldCase reports in surgery · 2018
    Article
  6. Adhesion Prevention Efficacy of Composite Meshes ParietexInternational journal of medical sciences · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Markus WinnyDepartment of General, Visceral and Transplant Surgery, Hannover Medical School Germany.
Lavinia MaegelInstitute for Pathology, Hannover Medical School Germany.
Leonie Victoria GretheDepartment of General, Visceral and Transplant Surgery, Hannover Medical School Germany.
Danny JonigkInstitute for Pathology, Hannover Medical School Germany.
Paul BorchertInstitute for Pathology, Hannover Medical School Germany.
Alexander KaltenbornCore Facility Quality Management and Health Technology Assessment in Transplantation, Integrated Research and Treatment Centre-Transplantation (IFB-Tx), Hannover Medical SchoolGermany; Department of Trauma and Orthopaedic Surgery, Federal Armed Forces Hospital WesterstedeWesterstede, Germany.
Harald SchremDepartment of General, Visceral and Transplant Surgery, Hannover Medical SchoolGermany; Core Facility Quality Management and Health Technology Assessment in Transplantation, Integrated Research and Treatment Centre-Transplantation (IFB-Tx), Hannover Medical SchoolGermany.
Juergen KlempnauerDepartment of General, Visceral and Transplant Surgery, Hannover Medical School Germany.
Daniel PoehnertDepartment of General, Visceral and Transplant Surgery, Hannover Medical School Germany.
Medizinische Hochschule Hannover · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIntraperitoneal onlay meshes (IPOM) can be associated with intestine-to-mesh adhesion formation, implementing risks like pain, enterocutaneous fistula, infection, and female infertility. This study investigates, whether a treatment of impaired intestinum with the anti-adhesive and hemostyptic agent 4DryField

methodsIn 20 male LEWIS rats uncoated polypropylene meshes were sewn to the inner abdominal wall and the cecum of the respective animal was de-peritonealized by peritoneal abrasion by a gauze swap, and meso-sutures ensured a constant contact of injured areas. Rats were treated with 4DryField

resultsTreatment of de-peritonealised cecum with 4DryField

conclusionThese experiments mimick clinical IPOM implantation scenarios with adjacent bowel depleted from peritoneum. 4DryField

Indexed as

4DryField® PHadhesion barrieradhesion preventionHernia mesh rat modelIPOMpolysaccharide

Identifiers

PMID28078041
PMCPMC5209521
OpenAlexW2969932477

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.