Evidence map›Paper›PMID 28078025›Full record

ArticleAmerican journal of translational research2016

Potential herb-drug interaction of shexiang baoxin pill in vitro based on drug metabolism/transporter.

Zhijie Shen, Yingjie Wang, Wei Guo, Yili Yao, Xiaolong Wang

Open access · greenAbstract read
PubMed Full text at PMC
In one paragraph

Article in American journal of translational research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Zhijie ShenCardiovascular Department, Shuguang Hospital Affiliated to Shanghai University of TCM Shanghai, China.
Yingjie WangCardiovascular Department, Shuguang Hospital Affiliated to Shanghai University of TCM Shanghai, China.
Wei GuoCardiovascular Department, Shuguang Hospital Affiliated to Shanghai University of TCM Shanghai, China.
Yili YaoCardiovascular Department, Shuguang Hospital Affiliated to Shanghai University of TCM Shanghai, China.
Xiaolong WangCardiovascular Department, Shuguang Hospital Affiliated to Shanghai University of TCM Shanghai, China.
Shanghai University of Traditional Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Many researches have proved functions of anti-oxidation, endothelial protection and pro-angiogenesis efficiency of Shexiang Baoxin Pill (SBP). This study aims to investigate potential for metabolism-based interaction on CYP450s and transporter based interaction on OATP1B1, BRCP and MDR1. Human primary hepatocytes were used in this study. Probe substrates of cytochrome P450 enzymes were incubated in human liver microsomes (HLMs) with or without SBP and IC

Indexed as

CYP450herb-drug interactionshexiang baoxin pilltransporters

Identifiers

PMID28078025
PMCPMC5209505
OpenAlexW2573441484

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.