Evidence map›Paper›PMID 28078021›Full record

ArticleAmerican journal of translational research2016

Micro RNA-19a suppresses thrombospondin-1 in CD35

Li-Tao Yang, Xiao-Xi Li, Shu-Qi Qiu, Lu Zeng, Lin-Jing Li, Bai-Sui Feng, Peng-Yuan Zheng, Zhi-Gang Liu, Ping-Chang Yang

Open access · greenAbstract read
In one paragraph

Article in American journal of translational research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.3field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Emerging functions of thrombospondin-1 in immunity.Seminars in cell & developmental biology · 2024
    Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Li-Tao YangThe Research Center of Allergy & Immunology, Shenzhen University School of MedicineShenzhen 518060, China; Shenzhen ENT Institute, Longgang ENT HospitalShenzhen 518116, China; Brain Body Institute, McMaster UniversityHamilton, ON L8N 4A6, Canada.
Xiao-Xi LiThe Research Center of Allergy & Immunology, Shenzhen University School of Medicine Shenzhen 518060, China.
Shu-Qi QiuThe Research Center of Allergy & Immunology, Shenzhen University School of MedicineShenzhen 518060, China; Shenzhen ENT Institute, Longgang ENT HospitalShenzhen 518116, China.
Lu ZengThe Research Center of Allergy & Immunology, Shenzhen University School of Medicine Shenzhen 518060, China.
Lin-Jing LiBrain Body Institute, McMaster UniversityHamilton, ON L8N 4A6, Canada; Department of Gastroenterology, The Second Hospital, Zhengzhou UniversityZhengzhou, China.
Bai-Sui FengDepartment of Gastroenterology, The Second Hospital, Zhengzhou University Zhengzhou, China.
Peng-Yuan ZhengDepartment of Gastroenterology, The Fifth Hospital, Zhengzhou University Zhengzhou, China.
Zhi-Gang LiuThe Research Center of Allergy & Immunology, Shenzhen University School of Medicine Shenzhen 518060, China.
Ping-Chang YangThe Research Center of Allergy & Immunology, Shenzhen University School of Medicine Shenzhen 518060, China.
Shenzhen University · CNLonggang Central Hospital · CNSecond Affiliated Hospital of Zhengzhou University · CNFifth Affiliated Hospital of Zhengzhou University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Disruption of immune tolerance is associated in the pathogenesis of allergy. Thrombospondin-1 (TSP1) plays a role in the maintenance of immune tolerance, which is compromised in allergic disorders. Micro RNA (miR) is involved in the regulation of immune responses. This study tests a hypothesis that miR-17-92 cluster is involved in the regulation of TSP1 in the intestinal CD35

Indexed as

B cellfood allergyintestineMicro RNA-19athrombospondin-1

Identifiers

PMID28078021
PMCPMC5209501
OpenAlexW2966313661

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.