Evidence map›Paper›PMID 28078016›Full record

ArticleAmerican journal of translational research2016

Trichosanatine alleviates oxidized low-density lipoprotein induced endothelial cells injury via inhibiting the LOX-1/p38 MAPK pathway.

Lei Zhang, Yu-Hua Jia, Xiao-Shan Zhao, Feng-Hua Zhou, Yun-Yun Pan, Qiang Wan, Xiao-Bing Cui, Xue-Gang Sun, Yu-Yao Chen, Yu Zhang and 1 more

Open access · greenAbstract read
In one paragraph

Article in American journal of translational research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 20 citations in OpenAlex.

  1. Recent advances in the role of gasotransmitters in necroptosis.Apoptosis : an international journal on programmed cell death · 2025
    Review
  2. Article
  3. Article
  4. Oxidized low-density lipoprotein stimulates dendritic cells maturation via LOX-1-mediated MAPK/NF-κB pathway.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2021
    Article
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  13. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Lei ZhangSchool of Traditional Chinese Medicine, Southern Medical University Guangzhou 510515, P. R. China.
Yu-Hua JiaSchool of Traditional Chinese Medicine, Southern Medical University Guangzhou 510515, P. R. China.
Xiao-Shan ZhaoSchool of Traditional Chinese Medicine, Southern Medical University Guangzhou 510515, P. R. China.
Feng-Hua ZhouSchool of Traditional Chinese Medicine, Southern Medical University Guangzhou 510515, P. R. China.
Yun-Yun PanSchool of Traditional Chinese Medicine, Southern Medical University Guangzhou 510515, P. R. China.
Qiang WanSchool of Traditional Chinese Medicine, Southern Medical University Guangzhou 510515, P. R. China.
Xiao-Bing CuiSchool of Traditional Chinese Medicine, Southern Medical University Guangzhou 510515, P. R. China.
Xue-Gang SunSchool of Traditional Chinese Medicine, Southern Medical University Guangzhou 510515, P. R. China.
Yu-Yao ChenSchool of Traditional Chinese Medicine, Southern Medical University Guangzhou 510515, P. R. China.
Yu ZhangSchool of Traditional Chinese Medicine, Southern Medical University Guangzhou 510515, P. R. China.
Sai-Bo ChengSchool of Traditional Chinese Medicine, Southern Medical University Guangzhou 510515, P. R. China.
Southern Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The LOX-1/p38 mitogen-activated protein kinase (MAPK) pathway has been proved to participate in the endothelial dysfunction in atherosclerosis. Trichosanatineis is an active compound isolated from the peel of

Indexed as

LOX-1oxidized low-density lipoproteinp38 mitogen-activated protein kinaseTrichosanatine

Identifiers

PMID28078016
PMCPMC5209496
OpenAlexW2576133281

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.