Evidence map›Paper›PMID 28077780›Full record

ArticleToxicological sciences : an official journal of the Society of Toxicology2017

Editor's Highlight: Exposure to CrVI during Early Pregnancy Increases Oxidative Stress and Disrupts the Expression of Antioxidant Proteins in Placental Compartments.

Sakhila K Banu, Jone A Stanley, Kirthiram K Sivakumar, Robert J Taylor, Joe A Arosh, Robert C Burghardt

Open access · greenAbstract read
In one paragraph

Article in Toxicological sciences : an official journal of the Society of Toxicology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
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  3. Association of exposure to PMFrontiers in public health · 2025
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  6. Biomarkers of metal toxicity in embryos in the general population.Journal of clinical laboratory analysis · 2019
    Article
  7. Article
  8. Sexually Dimorphic Impact of Chromium Accumulation on Human Placental Oxidative Stress and Apoptosis.Toxicological sciences : an official journal of the Society of Toxicology · 2018
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Sakhila K BanuDepartment of Veterinary Integrative Biosciences, College of Veterinary Medicine and Biomedical Sciences, Mail stop TAMU 4458, Texas A&M University, College Station, Texas 77843 skbanu@cvm.tamu.edu.
Jone A StanleyDepartment of Veterinary Integrative Biosciences, College of Veterinary Medicine and Biomedical Sciences, Mail stop TAMU 4458, Texas A&M University, College Station, Texas 77843.
Kirthiram K SivakumarDepartment of Veterinary Integrative Biosciences, College of Veterinary Medicine and Biomedical Sciences, Mail stop TAMU 4458, Texas A&M University, College Station, Texas 77843.
Robert J TaylorDepartment of Veterinary Integrative Biosciences, College of Veterinary Medicine and Biomedical Sciences, Mail stop TAMU 4458, Texas A&M University, College Station, Texas 77843.
Joe A AroshDepartment of Veterinary Integrative Biosciences, College of Veterinary Medicine and Biomedical Sciences, Mail stop TAMU 4458, Texas A&M University, College Station, Texas 77843.
Robert C BurghardtDepartment of Veterinary Integrative Biosciences, College of Veterinary Medicine and Biomedical Sciences, Mail stop TAMU 4458, Texas A&M University, College Station, Texas 77843.
Texas A&M University · US

Funding

TARGETED GENOMICS FACILITY COREP30ES023512 · NIEHS · TEXAS A&M AGRILIFE RESEARCH · PI THREADGILL, DAVID W. · 2014 to 2017
$3.3M
Mechanism of Prenatal Chromium-VI Exposure and Germ Cell Apoptosis in the OvaryR01ES025234 · NIEHS · TEXAS A&M AGRILIFE RESEARCH · PI BANU, SAKHILA · 2016 to 2020
$1.7M
ACQUISITION OF A CONFOCAL/MULTIPHOTON MICROSCOPY SYSTEMS10RR022532 · NCRR · TEXAS A&M UNIVERSITY · PI BURGHARDT, ROBERT C · 2006 to 2006
$499k
NCRR NIH HHS S10 RR022532NIEHS NIH HHS P30 ES023512NIEHS NIH HHS R01 ES025234
6 · The paper itself

Abstract

Epidemiologic studies document relationships between chromium VI (CrVI) exposure and increased risk of spontaneous abortion, stillbirth, preterm birth, and neonatal death in pregnant women. Environmental contamination with CrVI is a growing problem both in the United States and developing countries. CrVI is widely used in numerous industries. This study was designed to understand the mechanism of CrVI toxicity on placental oxidative stress and antioxidant (AOX) machinery. Pregnant mother rats were treated with or without CrVI (50 ppm K

Indexed as

Maternal ExposureOxidative StressAnimalsCell ProliferationChromiumEnvironmental PollutantsFemalePlacentaPregnancyRatsTrophoblastsChromiumchromium hexavalent ionEnvironmental PollutantsGpx1oxidative stressPrdx3.rat placenta and chromiumSodtrophoblast

Identifiers

PMID28077780
PMCPMC5291216
OpenAlexW2592175079

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.