Evidence map›Paper›PMID 28077700›Full record

ArticleJournal of clinical microbiology2017

Evaluation of Alere i RSV for Rapid Detection of Respiratory Syncytial Virus in Children Hospitalized with Acute Respiratory Tract Infection.

Rebecca Marie Peters, Sarah Valerie Schnee, Julia Tabatabai, Paul Schnitzler, Johannes Pfeil

Open access · hybridAbstract readComparative StudyEvaluation Study
In one paragraph

Article in Journal of clinical microbiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 40 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. [Association of temperament type and mother's emotional state with acute respiratory infection in children].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2022
    Article
  6. Article
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  9. Amplification chemistries in clinical virology.Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology · 2019
    Review
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Point-of-care diagnostics for respiratory viral infections.Expert review of molecular diagnostics · 2018
    Review
  16. Review
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Rebecca Marie PetersCenter for Childhood and Adolescent Medicine (General Pediatrics), University Hospital Heidelberg, Heidelberg, Germany.
Sarah Valerie SchneeCenter for Childhood and Adolescent Medicine (General Pediatrics), University Hospital Heidelberg, Heidelberg, Germany.
Julia TabatabaiCenter for Childhood and Adolescent Medicine (General Pediatrics), University Hospital Heidelberg, Heidelberg, Germany.
Paul SchnitzlerCenter for Infectious Diseases, Virology, University Hospital Heidelberg, Heidelberg, Germany.
Johannes PfeilCenter for Childhood and Adolescent Medicine (General Pediatrics), University Hospital Heidelberg, Heidelberg, Germany Johannes.Pfeil@med.uni-heidelberg.de.
German Center for Infection Research · DEHeidelberg University · DEUniversity Hospital Heidelberg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alere i RSV is a novel rapid test which applies a nicking enzyme amplification reaction to detect respiratory syncytial virus in point-of-care settings. In this study, we evaluated the Alere i RSV assay by using frozen nasopharyngeal swab samples that were collected in viral transport medium from children hospitalized with acute respiratory tract infection during the 2015-2016 winter season. Alere i RSV assay results were compared to those for Altona RealStar RSV real-time reverse transcription-PCR (RT-PCR). We found that the overall sensitivity and specificity of the Alere i RSV test was 100% (95% confidence intervals [CI], 93% to 100%) and 97% (95% CI, 89% to 100%), respectively. Positive samples were identified within 5 to 7 min from sample collection. Overall, the Alere i RSV test performed well compared to the RT-PCR assay and has the potential to facilitate the detection of RSV in point-of-care settings.

Indexed as

HospitalizationPoint-of-Care SystemsAdolescentChildChild, PreschoolFemaleHumansInfantMaleMolecular Diagnostic TechniquesNucleic Acid Amplification TechniquesProspective StudiesRespiratory Syncytial VirusesRespiratory Tract InfectionsSensitivity and SpecificityTime FactorsAlere i RSVpediatric infectious diseasepoint-of-carerapid testsrespiratory syncytial virusrespiratory tract infection

Identifiers

PMID28077700
PMCPMC5377829
OpenAlexW2574260127

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.