ArticleJournal of clinical microbiology2017
Point-Counterpoint: What Is the Optimal Approach for Detection of Clostridium difficile Infection?
Article in Journal of clinical microbiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
62 citing papers in PubMed, 4 syntheses or guidelines pooled it, 121 citations in OpenAlex.
- Clinical significance of toxin EIA positivity in patients with suspectedJournal of clinical microbiology · 2025Pooled it
- Evaluation of the Cepheid Xpert C. difficile diagnostic assay: an update meta-analysis.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2021Pooled it
- A Laboratory Medicine Best Practices Systematic Review and Meta-analysis of Nucleic Acid Amplification Tests (NAATs) and Algorithms Including NAATs for the Diagnosis ofClinical microbiology reviews · 2019Pooled it
- Diagnostic stewardship and the 2017 update of the IDSA-SHEA Clinical Practice Guidelines for Clostridium difficile Infection.Diagnosis (Berlin, Germany) · 2018Guideline
- Trial
- Rapid, Point-of-Care Microwave Lysis and Electrochemical Detection ofBioengineering (Basel, Switzerland) · 2024Article
- Impact of the Reverse 2-Step Algorithm forOpen forum infectious diseases · 2024Article
- Informing estimates of probability ofAntimicrobial stewardship & healthcare epidemiology : ASHE · 2024Article
- The impact of autocancellation of uncollectedInfection control and hospital epidemiology · 2023Article
- Assessing the Impact of 2-Step Clostridioides difficile Testing at the Healthcare Facility Level.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2023Article
- Evaluation of a two step testing algorithm to improve diagnostic accuracy and stewardship of Clostridioides difficile infections.BMC research notes · 2023Article
- Laboratory diagnosis of Clostridioides difficile infection in symptomatic patients: what can we do better?Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2023Article
- Budget Impact Analysis of Adopting a One-Step Nucleic Acid Amplification Testing (NAAT) Alone Diagnostic Pathway forDiagnostics (Basel, Switzerland) · 2023Article
- Diagnostic stewardship forAntimicrobial stewardship & healthcare epidemiology : ASHE · 2023Article
- Prevalence of diagnostically-discrepantFrontiers in medicine · 2023Article
- Association between prevalence of laboratory-identifiedInfection control and hospital epidemiology · 2022Article
- Low-toxinEmerging microbes & infections · 2022Article
- Ultrasensitive and Quantitative Toxin Measurement Correlates With Baseline Severity, Severe Outcomes, and Recurrence Among Hospitalized Patients With Clostridioides difficile Infection.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2022Article
- Clinical Outcomes of Treated and Untreated C. difficile PCR-Positive/Toxin-Negative Adult Hospitalized Patients: a Quasi-Experimental Noninferiority Study.Journal of clinical microbiology · 2022Article
- Binary Toxin Expression byOpen forum infectious diseases · 2022Article
2 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
INTRODUCTIONIn 2010, we published an initial Point-Counterpoint on the laboratory diagnosis of
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.