ArticleJournal of neurophysiology2017
Characterizing differential poststroke corticomotor drive to the dorsi- and plantarflexor muscles during resting and volitional muscle activation.
Article in Journal of neurophysiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
17 citing papers in PubMed, 22 citations in OpenAlex.
- Haptic interaction with a human partner for ankle training in chronic stroke: a pilot study.Journal of neuroengineering and rehabilitation · 2025Trial
- Relating cortical morphology, corticospinal excitability, corticomotor representation, and quadriceps strength after anterior cruciate ligament injury.Experimental brain research · 2025Article
- Delayed Cortical Responses During Reactive Balance After Stroke Associated With Slower Kinetics and Clinical Balance Dysfunction.Neurorehabilitation and neural repair · 2025Article
- Variability of corticospinal and spinal reflex excitability for the ankle dorsiflexor tibialis anterior across repeated measurements in people with and without incomplete spinal cord injury.Experimental brain research · 2024Article
- Delayed cortical engagement associated with balance dysfunction after stroke.medRxiv : the preprint server for health sciences · 2023Article
- Antagonist muscle torque at the ankle interfere with maximal voluntary contraction under isometric and anisometric conditions.Scientific reports · 2022Article
- Motor Cortical Network Flexibility is Associated With Biomechanical Walking Impairment in Chronic Stroke.Neurorehabilitation and neural repair · 2021Article
- The bilateral limb deficit (BLD) phenomenon during leg press: a preliminary investigation into central and peripheral factors.BMC sports science, medicine & rehabilitation · 2021Article
- Impaired interlimb coordination is related to asymmetries during pedaling after stroke.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2019Article
- Contribution of corticospinal drive to ankle plantar flexor muscle activation during gait in adults with cerebral palsy.Experimental brain research · 2019Article
- Bilateral Assessment of the Corticospinal Pathways of the Ankle Muscles Using Navigated Transcranial Magnetic Stimulation.Journal of visualized experiments : JoVE · 2019Article
- Modulatory Effects of Motor State During Paired Associative Stimulation on Motor Cortex Excitability and Motor Skill Learning.Frontiers in human neuroscience · 2019Article
- Brain imaging of locomotion in neurological conditions.Neurophysiologie clinique = Clinical neurophysiology · 2018Review
- Characterizing the corticomotor connectivity of the bilateral ankle muscles during rest and isometric contraction in healthy adults.Journal of electromyography and kinesiology : official journal of the International Society of Electrophysiological Kinesiology · 2018Article
- Association Between Altered Hip Extension and Kinetic Gait Variables.American journal of physical medicine & rehabilitation · 2018Article
- The use of transcranial magnetic stimulation to evaluate cortical excitability of lower limb musculature: Challenges and opportunities.Restorative neurology and neuroscience · 2018Review
- A novel low-cost approach for navigated transcranial magnetic stimulation.Restorative neurology and neuroscience · 2017Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
Imbalance of corticomotor excitability between the paretic and nonparetic limbs has been associated with the extent of upper extremity motor recovery poststroke, is greatly influenced by specific testing conditions such as the presence or absence of volitional muscle activation, and may vary across muscle groups. However, despite its clinical importance, poststroke corticomotor drive to lower extremity muscles has not been thoroughly investigated. Additionally, whereas conventional gait rehabilitation strategies for stroke survivors focus on paretic limb foot drop and dorsiflexion impairments, most contemporary literature has indicated that paretic limb propulsion and plantarflexion impairments are the most significant limiters to poststroke walking function. The purpose of this study was to compare corticomotor excitability of the dorsi- and plantarflexor muscles during resting and active conditions in individuals with good and poor poststroke walking recovery and in neurologically intact controls. We found that plantarflexor muscles showed reduced corticomotor symmetry between paretic and nonparetic limbs compared with dorsiflexor muscles in individuals with poor poststroke walking recovery during active muscle contraction but not during rest. Reduced plantarflexor corticomotor symmetry during active muscle contraction was a result of reduced corticomotor drive to the paretic muscles and enhanced corticomotor drive to the nonparetic muscles compared with the neurologically intact controls. These results demonstrate that atypical corticomotor drive exists in both the paretic and nonparetic lower limbs and implicate greater severity of corticomotor impairments to plantarflexor vs. dorsiflexor muscles during muscle activation in stroke survivors with poor walking recovery.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.