Evidence map›Paper›PMID 28077657›Full record

ArticleJournal of virology2017

Latent Membrane Protein 1 (LMP1) and LMP2A Collaborate To Promote Epstein-Barr Virus-Induced B Cell Lymphomas in a Cord Blood-Humanized Mouse Model but Are Not Essential.

Shi-Dong Ma, Ming-Han Tsai, James C Romero-Masters, Erik A Ranheim, Shane M Huebner, Jillian A Bristol, Henri-Jacques Delecluse, Shannon C Kenney

Open access · bronzeAbstract read
In one paragraph

Article in Journal of virology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
2.9field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 45 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Review
  9. Review
  10. Review
  11. Review
  12. Review
  13. Article
  14. Review
  15. Review
  16. Review
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Shi-Dong MaDepartment of Oncology, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Ming-Han TsaiDeutsches Krebsforschungszentrum and Inserm, Heidelberg, Germany.
James C Romero-MastersCellular and Molecular Pathology Graduate Program, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Erik A RanheimDepartment of Pathology, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Shane M HuebnerDepartment of Oncology, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Jillian A BristolDepartment of Oncology, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Henri-Jacques DelecluseDeutsches Krebsforschungszentrum and Inserm, Heidelberg, Germany.
Shannon C KenneyDepartment of Oncology, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, Wisconsin, USA skenney@wisc.edu.
University of Wisconsin–Madison · USDKFZ-ZMBH Alliance · DEGerman Cancer Research Center · DE

Funding

UW COMPREHENSIVE CANCER CENTER SUPPORTP30CA014520 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI AMY TRENTHAM-DIETZ · 1985 to 2026
$142.6M
Visualizing EBV and HCMV DNA Dynamics During InfectionP01CA022443 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI WILLIAM M. SUGDEN · 1985 to 2026
$53.1M
Training in Cancer Biology Training GrantT32CA009135 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI SUGDEN, WILLIAM M. · 1985 to 2024
$10.4M
GENE THERAPY FOR AIDS RELATED CNS LYMPHOMASR01CA066519 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI KENNEY, SHANNON CELESTE · 1995 to 2012
$3.7M
New Models and Treatments for AIDS-related LymphomaR01CA174462 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI KENNEY, SHANNON CELESTE · 2013 to 2017
$2.1M
NCI NIH HHS P01 CA022443NCI NIH HHS P30 CA014520NCI NIH HHS R01 CA066519NCI NIH HHS R01 CA174462
6 · The paper itself

Abstract

Epstein-Barr virus (EBV) infection is associated with B cell lymphomas in humans. The ability of EBV to convert human B cells into long-lived lymphoblastoid cell lines (LCLs)

Indexed as

AnimalsCells, CulturedCell Transformation, NeoplasticEpstein-Barr Virus InfectionsGene Knockout TechniquesHerpesvirus 4, HumanHumansLymphocytes, Tumor-InfiltratingLymphoma, Large B-Cell, DiffuseMice, Inbred NODMice, SCIDViral Matrix ProteinsEBV-associated membrane antigen, Epstein-Barr virusViral Matrix ProteinsEBVEpstein-Barr virushumanized mouseLMP1LMP2Alymphoma

Identifiers

PMID28077657
PMCPMC5355617
OpenAlexW2579700312

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.