Evidence map›Paper›PMID 28077628›Full record

ArticleThe Journal of biological chemistry2017

The Creatininase Homolog MftE from

Nathan A Bruender, Vahe Bandarian

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. ACS chemical biology · 2022
    Article
  5. Article
  6. Impact of Oxygen Supply and Scale Up onFrontiers in bioengineering and biotechnology · 2020
    Article
  7. Article
  8. Article
  9. Occurrence, function, and biosynthesis of mycofactocin.Applied microbiology and biotechnology · 2019
    Review
  10. Article
  11. Review
  12. Mechanistic elucidation of the mycofactocin-biosynthetic radicalThe Journal of biological chemistry · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Nathan A BruenderFrom the Department of Chemistry, University of Utah, Salt Lake City, Utah 84112.
Vahe BandarianFrom the Department of Chemistry, University of Utah, Salt Lake City, Utah 84112 vahe@chem.utah.edu.
University of Utah · US

Funding

Biosynthesis of Deazapurine-Containing MetabolitesR01GM072623 · NIGMS · UNIVERSITY OF UTAH · PI BANDARIAN, VAHE · 2005 to 2017
$3.9M
Mechanistic studies of thioether crosslink formation in peptidesR01GM120638 · NIGMS · UNIVERSITY OF UTAH · PI BANDARIAN, VAHE · 2016 to 2017
$695k
NIGMS NIH HHS R01 GM072623NIGMS NIH HHS R01 GM120638
6 · The paper itself

Abstract

Most ribosomally synthesized and post-translationally modified peptide (RiPP) natural products are processed by tailoring enzymes to create complex natural products that are still recognizably peptide-based. However, some tailoring enzymes dismantle the peptide en route to synthesis of small molecules. A small molecule natural product of as yet unknown structure, mycofactocin, is thought to be synthesized in this way via the

Indexed as

Protein Processing, Post-TranslationalAmino Acid SequenceBacterial ProteinsCatalysisCrystallography, X-RayMycobacterium smegmatisOxidation-ReductionPeptide FragmentsRibosomesSequence Homology, Amino AcidSubstrate SpecificityUreohydrolasesBacterial ProteinscreatinasePeptide FragmentsUreohydrolasesenzyme catalysisenzyme mechanismnatural product biosynthesisproteolytic enzymesecondary metabolism

Identifiers

PMID28077628
PMCPMC5354501
OpenAlexW2573172952

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.