ArticleOpen biology2017
The neuroendocrine immunomodulatory axis-like pathway mediated by circulating haemocytes in pacific oyster Crassostrea gigas.
Article in Open biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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Who cites it
9 citing papers in PubMed, 55 citations in OpenAlex.
- Transcriptomic responses in the nervous system and correlated behavioural changes of a cephalopod exposed to ocean acidification.BMC genomics · 2024Article
- Inflammation: A New Look at an Old Problem.International journal of molecular sciences · 2022Review
- RGD-Labeled Hemocytes With High Migration Activity Display a Potential Immunomodulatory Role in the Pacific OysterFrontiers in immunology · 2022Article
- Type II Grass Carp Reovirus Infects Leukocytes but Not Erythrocytes and Thrombocytes in Grass Carp (Viruses · 2021Article
- High temperature induces transcriptomic changes inThe Journal of experimental biology · 2020Article
- Transcriptional changes in the Japanese scallop (Mizuhopecten yessoensis) shellinfested by Polydora provide insights into the molecular mechanism of shell formation and immunomodulation.Scientific reports · 2018Article
- Article
- The Neuroendocrine-Immune Regulation in Response to Environmental Stress in Marine Bivalves.Frontiers in physiology · 2018Review
- The Cholinergic and Adrenergic Autocrine Signaling Pathway Mediates Immunomodulation in OysterFrontiers in immunology · 2018Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The neuroendocrine-immune (NEI) regulatory network is a complex system, which plays an indispensable role in the immunity of host. In this study, a neuroendocrine immunomodulatory axis (NIA)-like pathway mediated by the nervous system and haemocytes was characterized in the oyster Crassostrea gigas Once invaded pathogen was recognized by the host, the nervous system would temporally release neurotransmitters to modulate the immune response. Instead of acting passively, oyster haemocytes were able to mediate neuronal immunomodulation promptly by controlling the expression of specific neurotransmitter receptors on cell surface and modulating their binding sensitivities, thus regulating intracellular concentration of Ca
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Registered trials
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