GuidelineNeurology2017
Practice guideline summary: Use of fMRI in the presurgical evaluation of patients with epilepsy: Report of the Guideline Development, Dissemination, and Implementation Subcommittee of the American Academy of Neurology.
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In one paragraph
Guideline in Neurology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 113 papers, 5 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
113citing papers in PubMed, 5 pooled it
19.8field-weighted citation impact, top 1% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
113 citing papers in PubMed, 5 syntheses or guidelines pooled it, 242 citations in OpenAlex.
- Is functional MRI a reliable surrogate for the Wada test for preoperative assessment of hemispheric language laterality in pediatric patients? A systematic review and meta-analysis.Neuroradiology · 2025Pooled it
- Pooled it
- Roles of fMRI and Wada tests in the presurgical evaluation of language functions in temporal lobe epilepsy.Frontiers in neurology · 2022Pooled it
- A quantitative approach for measuring laterality in clinical fMRI for preoperative language mapping.Neuroradiology · 2021Pooled it
- Comparing the Intracarotid Amobarbital Test and Functional MRI for the Presurgical Evaluation of Language in Epilepsy.Current neurology and neuroscience reports · 2017Pooled it
- A systematic review of the impact of stimulus presentation modality on fMRI studies for presurgical mapping.Neuroimage. Reports · 2026Review
- Mapping without tasks: resting-state fMRI for motor and language localization in neuro-oncology.Neuroradiology · 2026Article
- Individual-specific resting-state networks predict language dominance in drug-resistant epilepsy.Epilepsia · 2026Article
- Leveraging Task FMRI Data to Extract Resting-State Metrics in Brain Tumor and Healthy Populations.Clinical neuroradiology · 2026Article
- Case report: precise mapping and epilepsy surgery of the Broca's area after a comprehensive OPM-MEG investigation of Broca's area localization.Acta epileptologica · 2026Article
- Face-name associative memory in temporal lobe epilepsy: Region-specific insights in right-hemisphere onset.Epilepsy research · 2026Article
- Leveraging neuroscience imaging and electrophysiological assessments to decode neuron-glioma interactions.Neuro-oncology advances · 2026Review
- Metabolic connectivity and memory in mesial temporal lobe epilepsy.Brain communications · 2026Article
- Does white matter structure relate to hemispheric language lateralization? A systematic review.Brain communications · 2026Review
- Multimodal neuroimaging fusion in presurgical evaluation of drug-resistant epilepsy: current evidence, clinical integration, and future directions.Frontiers in neuroscience · 2026Review
- MICAFlow: Fast and robust MRI preprocessing bridging research neuroimaging and clinical practice.Imaging neuroscience (Cambridge, Mass.) · 2026Article
- The Neural Cost of Language Processing: Broader Network Recruitment in Adults With Developmental Language Disorder.Neurobiology of language (Cambridge, Mass.) · 2026Article
- Review
- Individual-specific resting-state networks predict language dominance in drug-resistant epilepsy.medRxiv : the preprint server for health sciences · 2025Article
- Epilepsy Surgery in Kazakhstan: Outcomes and the Role of Advanced Imaging.Journal of clinical medicine · 2025Article
53 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
11 authors at 8 institutions in 1 country.
Jerzy P SzaflarskiFrom the Department of Neurology (J.P.S.), University of Alabama at Birmingham; Department of Neurology (D.G.), Charleston Area Medical Center, WV; Department of Neurology (J.R.B., S.J.S.), Medical College of Wisconsin, Milwaukee; Children's National Medical Center (W.D.G.), George Washington University, Washington, DC; Departments of Neurosurgery and Radiology (A.J.G.), Brigham and Women's Hospital, Boston, MA; Cincinnati Children's Hospital Research Foundation (S.K.H.), OH; Department of Neurosurgery (J.O.), Seattle Children's Hospital, WA; Department of Neurology (D.C.S.), Oregon Health & Science University, Portland; Department of Neurology (J.A.F.), New York University, New York; and Clinical Epilepsy Section (W.H.T.), National Institute of Neurological Disorders and Stroke, NIH, Bethesda, MD.
David GlossFrom the Department of Neurology (J.P.S.), University of Alabama at Birmingham; Department of Neurology (D.G.), Charleston Area Medical Center, WV; Department of Neurology (J.R.B., S.J.S.), Medical College of Wisconsin, Milwaukee; Children's National Medical Center (W.D.G.), George Washington University, Washington, DC; Departments of Neurosurgery and Radiology (A.J.G.), Brigham and Women's Hospital, Boston, MA; Cincinnati Children's Hospital Research Foundation (S.K.H.), OH; Department of Neurosurgery (J.O.), Seattle Children's Hospital, WA; Department of Neurology (D.C.S.), Oregon Health & Science University, Portland; Department of Neurology (J.A.F.), New York University, New York; and Clinical Epilepsy Section (W.H.T.), National Institute of Neurological Disorders and Stroke, NIH, Bethesda, MD.
Jeffrey R BinderFrom the Department of Neurology (J.P.S.), University of Alabama at Birmingham; Department of Neurology (D.G.), Charleston Area Medical Center, WV; Department of Neurology (J.R.B., S.J.S.), Medical College of Wisconsin, Milwaukee; Children's National Medical Center (W.D.G.), George Washington University, Washington, DC; Departments of Neurosurgery and Radiology (A.J.G.), Brigham and Women's Hospital, Boston, MA; Cincinnati Children's Hospital Research Foundation (S.K.H.), OH; Department of Neurosurgery (J.O.), Seattle Children's Hospital, WA; Department of Neurology (D.C.S.), Oregon Health & Science University, Portland; Department of Neurology (J.A.F.), New York University, New York; and Clinical Epilepsy Section (W.H.T.), National Institute of Neurological Disorders and Stroke, NIH, Bethesda, MD.
William D GaillardFrom the Department of Neurology (J.P.S.), University of Alabama at Birmingham; Department of Neurology (D.G.), Charleston Area Medical Center, WV; Department of Neurology (J.R.B., S.J.S.), Medical College of Wisconsin, Milwaukee; Children's National Medical Center (W.D.G.), George Washington University, Washington, DC; Departments of Neurosurgery and Radiology (A.J.G.), Brigham and Women's Hospital, Boston, MA; Cincinnati Children's Hospital Research Foundation (S.K.H.), OH; Department of Neurosurgery (J.O.), Seattle Children's Hospital, WA; Department of Neurology (D.C.S.), Oregon Health & Science University, Portland; Department of Neurology (J.A.F.), New York University, New York; and Clinical Epilepsy Section (W.H.T.), National Institute of Neurological Disorders and Stroke, NIH, Bethesda, MD.
Alexandra J GolbyFrom the Department of Neurology (J.P.S.), University of Alabama at Birmingham; Department of Neurology (D.G.), Charleston Area Medical Center, WV; Department of Neurology (J.R.B., S.J.S.), Medical College of Wisconsin, Milwaukee; Children's National Medical Center (W.D.G.), George Washington University, Washington, DC; Departments of Neurosurgery and Radiology (A.J.G.), Brigham and Women's Hospital, Boston, MA; Cincinnati Children's Hospital Research Foundation (S.K.H.), OH; Department of Neurosurgery (J.O.), Seattle Children's Hospital, WA; Department of Neurology (D.C.S.), Oregon Health & Science University, Portland; Department of Neurology (J.A.F.), New York University, New York; and Clinical Epilepsy Section (W.H.T.), National Institute of Neurological Disorders and Stroke, NIH, Bethesda, MD.
Scott K HollandFrom the Department of Neurology (J.P.S.), University of Alabama at Birmingham; Department of Neurology (D.G.), Charleston Area Medical Center, WV; Department of Neurology (J.R.B., S.J.S.), Medical College of Wisconsin, Milwaukee; Children's National Medical Center (W.D.G.), George Washington University, Washington, DC; Departments of Neurosurgery and Radiology (A.J.G.), Brigham and Women's Hospital, Boston, MA; Cincinnati Children's Hospital Research Foundation (S.K.H.), OH; Department of Neurosurgery (J.O.), Seattle Children's Hospital, WA; Department of Neurology (D.C.S.), Oregon Health & Science University, Portland; Department of Neurology (J.A.F.), New York University, New York; and Clinical Epilepsy Section (W.H.T.), National Institute of Neurological Disorders and Stroke, NIH, Bethesda, MD.
Jeffrey OjemannFrom the Department of Neurology (J.P.S.), University of Alabama at Birmingham; Department of Neurology (D.G.), Charleston Area Medical Center, WV; Department of Neurology (J.R.B., S.J.S.), Medical College of Wisconsin, Milwaukee; Children's National Medical Center (W.D.G.), George Washington University, Washington, DC; Departments of Neurosurgery and Radiology (A.J.G.), Brigham and Women's Hospital, Boston, MA; Cincinnati Children's Hospital Research Foundation (S.K.H.), OH; Department of Neurosurgery (J.O.), Seattle Children's Hospital, WA; Department of Neurology (D.C.S.), Oregon Health & Science University, Portland; Department of Neurology (J.A.F.), New York University, New York; and Clinical Epilepsy Section (W.H.T.), National Institute of Neurological Disorders and Stroke, NIH, Bethesda, MD.
David C SpencerFrom the Department of Neurology (J.P.S.), University of Alabama at Birmingham; Department of Neurology (D.G.), Charleston Area Medical Center, WV; Department of Neurology (J.R.B., S.J.S.), Medical College of Wisconsin, Milwaukee; Children's National Medical Center (W.D.G.), George Washington University, Washington, DC; Departments of Neurosurgery and Radiology (A.J.G.), Brigham and Women's Hospital, Boston, MA; Cincinnati Children's Hospital Research Foundation (S.K.H.), OH; Department of Neurosurgery (J.O.), Seattle Children's Hospital, WA; Department of Neurology (D.C.S.), Oregon Health & Science University, Portland; Department of Neurology (J.A.F.), New York University, New York; and Clinical Epilepsy Section (W.H.T.), National Institute of Neurological Disorders and Stroke, NIH, Bethesda, MD.
Sara J SwansonFrom the Department of Neurology (J.P.S.), University of Alabama at Birmingham; Department of Neurology (D.G.), Charleston Area Medical Center, WV; Department of Neurology (J.R.B., S.J.S.), Medical College of Wisconsin, Milwaukee; Children's National Medical Center (W.D.G.), George Washington University, Washington, DC; Departments of Neurosurgery and Radiology (A.J.G.), Brigham and Women's Hospital, Boston, MA; Cincinnati Children's Hospital Research Foundation (S.K.H.), OH; Department of Neurosurgery (J.O.), Seattle Children's Hospital, WA; Department of Neurology (D.C.S.), Oregon Health & Science University, Portland; Department of Neurology (J.A.F.), New York University, New York; and Clinical Epilepsy Section (W.H.T.), National Institute of Neurological Disorders and Stroke, NIH, Bethesda, MD.
Jacqueline A FrenchFrom the Department of Neurology (J.P.S.), University of Alabama at Birmingham; Department of Neurology (D.G.), Charleston Area Medical Center, WV; Department of Neurology (J.R.B., S.J.S.), Medical College of Wisconsin, Milwaukee; Children's National Medical Center (W.D.G.), George Washington University, Washington, DC; Departments of Neurosurgery and Radiology (A.J.G.), Brigham and Women's Hospital, Boston, MA; Cincinnati Children's Hospital Research Foundation (S.K.H.), OH; Department of Neurosurgery (J.O.), Seattle Children's Hospital, WA; Department of Neurology (D.C.S.), Oregon Health & Science University, Portland; Department of Neurology (J.A.F.), New York University, New York; and Clinical Epilepsy Section (W.H.T.), National Institute of Neurological Disorders and Stroke, NIH, Bethesda, MD.
William H TheodoreFrom the Department of Neurology (J.P.S.), University of Alabama at Birmingham; Department of Neurology (D.G.), Charleston Area Medical Center, WV; Department of Neurology (J.R.B., S.J.S.), Medical College of Wisconsin, Milwaukee; Children's National Medical Center (W.D.G.), George Washington University, Washington, DC; Departments of Neurosurgery and Radiology (A.J.G.), Brigham and Women's Hospital, Boston, MA; Cincinnati Children's Hospital Research Foundation (S.K.H.), OH; Department of Neurosurgery (J.O.), Seattle Children's Hospital, WA; Department of Neurology (D.C.S.), Oregon Health & Science University, Portland; Department of Neurology (J.A.F.), New York University, New York; and Clinical Epilepsy Section (W.H.T.), National Institute of Neurological Disorders and Stroke, NIH, Bethesda, MD.
Seattle Children's Hospital · USNew York University · USCharleston Area Medical Center · USChildren's Hospital Foundation · USChildren's National · USMedical College of Wisconsin · USOregon Health & Science University · USUniversity of Alabama at Birmingham · US
Funding
Physiologic And Pharmacologic Studies In EpilepsyZIANS002236 · NINDS · NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE · PI THEODORE, WILLIAM · 2009 to 2020
$14.2MAbstract
objectiveTo assess the diagnostic accuracy and prognostic value of functional MRI (fMRI) in determining lateralization and predicting postsurgical language and memory outcomes.
methodsAn 11-member panel evaluated and rated available evidence according to the 2004 American Academy of Neurology process. At least 2 panelists reviewed the full text of 172 articles and selected 37 for data extraction. Case reports, reports with <15 cases, meta-analyses, and editorials were excluded. RESULTS AND RECOMMENDATIONS: The use of fMRI may be considered an option for lateralizing language functions in place of intracarotid amobarbital procedure (IAP) in patients with medial temporal lobe epilepsy (MTLE; Level C), temporal epilepsy in general (Level C), or extratemporal epilepsy (Level C). For patients with temporal neocortical epilepsy or temporal tumors, the evidence is insufficient (Level U). fMRI may be considered to predict postsurgical language deficits after anterior temporal lobe resection (Level C). The use of fMRI may be considered for lateralizing memory functions in place of IAP in patients with MTLE (Level C) but is of unclear utility in other epilepsy types (Level U). fMRI of verbal memory or language encoding should be considered for predicting verbal memory outcome (Level B). fMRI using nonverbal memory encoding may be considered for predicting visuospatial memory outcomes (Level C). Presurgical fMRI could be an adequate alternative to IAP memory testing for predicting verbal memory outcome (Level C). Clinicians should carefully advise patients of the risks and benefits of fMRI vs IAP during discussions concerning choice of specific modality in each case.
Indexed as
Magnetic Resonance ImagingPreoperative CareBrainBrain MappingEpilepsyFunctional LateralityHumansLanguageMemoryPostoperative Complications
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.