ArticleJournal of the American Heart Association2017
Impact of Sex and Contact-to-Device Time on Clinical Outcomes in Acute ST-Segment Elevation Myocardial Infarction-Findings From the National Cardiovascular Data Registry.
Article in Journal of the American Heart Association, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
36 citing papers in PubMed, 62 citations in OpenAlex.
- Sex differences in rural prehospital ST-segment elevation myocardial infarction care.Emergency medicine journal : EMJ · 2026Article
- Persistent Sex Disparities in Pre-Hospital Delay Among Patients With STEMI Despite Overall Improvements: Findings From the Chinese Cardiovascular Association Chest Pain Center Registry.Journal of the American Heart Association · 2026Article
- Intra-aortic Balloon Pump Utilization Prior to Coronary Artery Bypass Grafting: Social Determinants of Health.Journal of the Society for Cardiovascular Angiography & Interventions · 2026Article
- Redesigning medicine: integrating sex and gender for better health outcomes.Naunyn-Schmiedeberg's archives of pharmacology · 2026Review
- Evolution of Critical Care Cardiology: An Update on Structure, Care Delivery, Training, and Research Paradigms: A Scientific Statement From the American Heart Association.Journal of the American College of Cardiology · 2025Article
- Unequal disease burdens: exploring the intersection of gender, health and disease dynamics in China.BMC public health · 2025Article
- Sex-related differences in care and prognosis in acute coronary syndrome.Preventive medicine reports · 2025Article
- Sex disparities in diagnostic workup of benign pancreaticobiliary disease before endoscopic retrograde cholangiopancreatography.iGIE : innovation, investigation and insights · 2025Article
- Review
- Demographics and regional trends of ischemic heart disease-related mortality in older adults in the United States, 1999-2020.PloS one · 2025Article
- Feedback Loop Failure Modes in Medical Diagnosis: How Biases Can Emerge and Be Reinforced.Medical decision making : an international journal of the Society for Medical Decision Making · 2024Article
- Sex Disparities After Coronary Artery Bypass Grafting and Hospital Quality.JAMA network open · 2024Article
- Sex Differences in Heart Failure: What Do We Know?Journal of cardiovascular development and disease · 2023Review
- Mortality of patients with ST-segment-elevation myocardial infarction without standard modifiable risk factors among patients without known coronary artery disease: Age-stratified and sex-related analysis from nationwide readmissions database 2010-2014.American journal of preventive cardiology · 2023Article
- Sex differences in time to primary percutaneous coronary intervention and outcomes in patients presenting with ST-segment elevation myocardial infarction.Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2022Article
- Sex-Specific Considerations in the Presentation, Diagnosis, and Management of Ischemic Heart Disease: JACC Focus Seminar 2/7.Journal of the American College of Cardiology · 2022Review
- Review
- Trends in outcomes of women with myocardial infarction undergoing primary angioplasty-Analysis of randomized trials.Frontiers in cardiovascular medicine · 2022Article
- Gender-Disparities in the in-Hospital Clinical Outcome Among Patients with Chronic Kidney Disease Undergoing Percutaneous Coronary Intervention.International journal of general medicine · 2022Article
- Delays to Hospital Presentation in Women and Men with ST-Segment Elevation Myocardial Infarction: A Multi-Center Analysis of Patients Hospitalized in New York City.Therapeutics and clinical risk management · 2022Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundEmergent myocardial reperfusion via primary percutaneous coronary intervention is optimal care for patients presenting with ST-segment elevation myocardial infarction (STEMI). Delays in such interventions are associated with increases in mortality. With the shift in focus to contact-to-device (C2D) time as a new perfusion metric, this study was designed to examine how sex affects C2D time and mortality in STEMI patients. METHODS AND
resultsClinical data on male and female STEMI patients were extracted and analyzed from the National Cardiovascular Data Registry from July 1, 2008 to December 31, 2014. A total of 102 515 patients were included in the final analytic cohort. The median C2D time in female patients with STEMI was delayed when compared to male patients (80 [65-97] versus 75 [61-90] minutes; P<0.001). The unadjusted mortality was higher in female patients when compared to male patients with STEMI (4.1% versus 2.0%; P<0.001). For every 5-minute increase in C2D time, the adjusted odds ratio for mortality was 1.04 (95% CI, 1.03-1.06) for female patients with STEMI and 1.07 (95% CI, 1.06-1.09) for male patients (P for sex by C2D interaction=0.003).
conclusionsTo date, this is the largest analysis of STEMI patients that measures the impact of the new recommended C2D reperfusion metric on in-hospital mortality. Female STEMI patients have longer C2D times and increased mortality. The disparity can be improved and survival can increase in this high-risk patient cohort by decreasing systems issues that cause increased reperfusion times in female STEMI patients.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.