ArticleBMC gastroenterology2017
The cut-off value of tumor size and appropriate timing of follow-up for management of minimal EUS-suspected gastric gastrointestinal stromal tumors.
Article in BMC gastroenterology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.
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Who cites it
31 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Practice Guidelines for the Diagnosis and Treatment of Subepithelial Lesion Observed in Upper Gastrointestinal Endoscopy.Journal of gastroenterology and hepatology · 2026Guideline
- Correlation between imaging features and pathological risk of gastric stromal tumors in endoscopic ultrasonography and enhanced computed tomography.BMC gastroenterology · 2026Article
- Nationwide Multicenter Study of Advanced Endoscopic Resection and Malignant Risk Model for Gastric Myogenic Tumors (GASTRO Trial).Life (Basel, Switzerland) · 2026Article
- Natural Course of Gastric Subepithelial Tumors.The Korean journal of helicobacter and upper gastrointestinal research · 2025Review
- Serum Pepsinogen as a Biomarker of Gastrointestinal Stromal Tumors (GIST) in Stomach.Cancer medicine · 2025Article
- Practice Guidelines for the Diagnosis and Treatment of Subepithelial Lesions Observed in Upper Gastrointestinal Endoscopy.The Korean journal of helicobacter and upper gastrointestinal research · 2025Review
- Endoscopic full-thickness resectionWorld journal of gastrointestinal surgery · 2025Article
- Natural Course and Long-Term Outcomes of Gastric Subepithelial Lesions: A Systematic Review.Journal of clinical medicine · 2025Review
- Patterns of Care and Outcomes of Patients with Small Gastrointestinal Stromal Tumors at a High-Volume Sarcoma Center.Annals of surgical oncology · 2024Article
- Article
- Rapidly Growing, High-Risk Gastrointestinal Stromal Tumor of the Stomach: A Case Report.The Korean journal of helicobacter and upper gastrointestinal research · 2023Article
- Prevalence, natural progression, and clinical practices of upper gastrointestinal subepithelial lesions in Korea: a multicenter study.Clinical endoscopy · 2023Article
- Could tumour volume and major and minor axis based on CTA statistical anatomy improve the pre-operative T-stage in oesophageal cancer?Cancer medicine · 2023Article
- Small Gastric Stromal Tumors: An Underestimated Risk.Cancers · 2022Article
- Efficacy of endoscopic ultrasound in the evaluation of small gastrointestinal stromal tumors.World journal of gastroenterology · 2022Article
- The necessarity of treatment for small gastric subepithelial tumors (1-2 cm) originating from muscularis propria: an analysis of 972 tumors.BMC gastroenterology · 2022Article
- Efficiency of an endoscopic resection strategy for management of submucosal tumors < 20 mm in the upper gastrointestinal tract.Endoscopy international open · 2022Article
- The Diagnosis of Small Gastrointestinal Subepithelial Lesions by Endoscopic Ultrasound-Guided Fine Needle Aspiration and Biopsy.Diagnostics (Basel, Switzerland) · 2022Review
- Advances in endoscopic resection techniques of small gastric tumors originating from the muscularis propria.Frontiers in oncology · 2022Article
- Efficacy and safety of endoscopic resection in treatment of small gastric stromal tumors: A state-of-the-art review.World journal of gastrointestinal oncology · 2021Review
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Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroudThe detectable rate of minimal gastric GISTs has continuously increased. While the surveillance and management of GIST <2 cm have been deemed controversial or lack evidence-based approaches. The aim of the current study is to propose a cut-off value of tumor size for treatment policy and the appropriate timing for endoscopic ultrasonography (EUS) follow-up in the minimal EUS-suspected gastric GIST patients.
methodsA single-institution retrospective study was performed. 69 patients with EUS-suspected gastric GISTs were studied from November 2008 to March 2015. 69 patients with minimal gastric GISTs ≤2 cm diagnosed by EUS were followed for a mean period of 29 months (range, 12 to 70). An at least 20% increase of the maximal diameter of the tumors was set as a significant change.
resultsDuring follow-up, Of the 69 minimal EUS-suspected GISTs, 16 (23.2%) showed significant changes in size. 11 out of 69 GISTs (15.9%), 6 out of 43 GISTs (14.0%), 7 out of 30 GISTs (23.3%) showed significant changes in size, at 1 year, 2 years, and more than 3 years respectively. The receiver operating characteristic curve analysis showed that the tumor size cut-off was 9.5 mm. Only 4.7 and 3.7% of gastric EUS-suspected GISTs of <9.5 mm in size showed significant changes at 1 year and 2 years, while 9.5% at more than 3 years. 34.6, 31.3 and 55.6% of gastric EUS-suspected GISTs of ≥ 9.5 mm in size showed significant changes at 1 year, 2 years and more than 3 years.
conclusionsMinimal EUS-suspected GISTs, larger than 9.5 mm may be associated with significant progression. The patients with a ≥ 9.5 mm GIST should have a EUS 6-12months, while <9.5 mm GIST may have a EUS extended to every 2-3 years.
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