ArticleActa orthopaedica2017
Is decreasing mortality in total hip and knee arthroplasty patients dependent on patients' comorbidity?
Article in Acta orthopaedica, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.
- Thromboprophylaxis with enoxaparin and direct oral anticoagulants in major orthopedic surgery and acutely ill medical patients: a meta-analysis.Internal and emergency medicine · 2017Pooled it
- Bariatric Surgery Decreases the Risk of Non-traffic Accident-Related Fractures in Patients with Obesity: Real-world Data from Taiwan.Obesity surgery · 2021Trial
- Analysis of risk factors for lower deep vein thrombosis (DVT) in patients over 60 years of age after total hip arthroplasty.BMC musculoskeletal disorders · 2025Article
- Graft failure within 2 years of isolated anterior cruciate ligament reconstruction is associated with increased risk of secondary meniscus tears.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2023Article
- Clinical Frailty Scale is a better predictor for adverse post-operative complications and functional outcomes than Modified Frailty Index and Charlson Comorbidity Index after total knee arthroplasty.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2023Article
- Efficacy and Safety Study of Low-Molecular-Weight Heparin and Fondaparinux Sodium After Hip Arthroplasty: A Retrospective Cohort Study.Orthopedic research and reviews · 2023Article
- Effects of Comorbidities on Pain and Function After Total Hip Arthroplasty.Frontiers in surgery · 2022Article
- [Rehabilitation following total knee replacement].Der Orthopade · 2021Review
- Incidence and risk factors analysis for mortality after total knee arthroplasty based on a large national database in Korea.Scientific reports · 2021Article
- The Update on Instruments Used for Evaluation of Comorbidities in Total Hip Arthroplasty.Indian journal of orthopaedics · 2021Review
- Increased rate of complications in myasthenia gravis patients following hip and knee arthroplasty: a nationwide database study in the PearlDiver Database on 257,707 patients.Acta orthopaedica · 2021Article
- Preoperative femoral vein velocity in maximal flexion is a predictor of deep vein thrombosis in patients undergoing total hip arthroplasty.Acta clinica Croatica · 2020Article
- Impact of comorbidity on the short- and medium-term risk of revision in total hip and knee arthroplasty.BMC musculoskeletal disorders · 2020Article
- Complications in Total Joint Arthroplasties.Journal of clinical medicine · 2019Article
- Risk of further surgery on the same or opposite side and mortality after primary total hip arthroplasty: A multi-state analysis of 133,654 patients from the Swedish Hip Arthroplasty Register.Acta orthopaedica · 2018Article
- Fast-tracking for total knee replacement reduces use of institutional care without compromising quality.Acta orthopaedica · 2018Article
- Liver disease and mortality among patients with hip fracture: a population-based cohort study.Clinical epidemiology · 2018Article
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background and purpose - Mortality after primary total hip and knee arthroplasty (THA and TKA) has declined, and the proportion of THA and TKA patients with comorbid conditions has increased. We therefore wanted to examine changes in comorbidity burden over time and the impact of comorbid on mortality following primary total hip and knee arthroplasty in patients with osteoarthritis. Patients and methods - We used the Danish arthroplasty registers to identify THA and TKA patients from 1996 through 2013. From administrative databases, we collected data on pre-surgery hospital history for all patients, which were used to calculate the Charlson comorbidity index (CCI). Patients were divided into 4 groups: CCI-none, CCI-low, CCI-moderate, and CCI-high. We calculated the relative risk (RR) of mortality within 90 days after surgery with a 95% confidence interval (CI), with stratification according to CCI group and year of surgery. Results - 99,962 THAs and 63,718 TKAs were included. The proportion of THAs with comorbidity increased by 3-4% in CCI-low, CCI-moderate, and CCI-high patients, from 1996-1999 to 2010-2013. The overall 90-day mortality risk declined for both procedures. Compared to CCI-none, THA patients with low, moderate, and high comorbidity burdens had an RR of 90-day mortality of 1.9 (95% CI: 1.6-2.4), 1.9 (CI: 1.5-2.5), and 3.3 (CI: 2.6-4.2), respectively. Similar increases in proportions and RRs were observed in TKAs. Interpretation - Despite the fact that the proportion of THA and TKA patients with comorbidities has increased over the past 18 years, the overall mortality has declined. The mortality risk depended on the comorbidity burden and did not decline during the study period for THA and TKA patients with a moderate or high comorbidity burden at the time of surgery.
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