Evidence map›Paper›PMID 28076848›Full record

ArticleOncotarget2017

Endovascular brachytherapy combined with portal vein stenting and transarterial chemoembolization improves overall survival of hepatocellular carcinoma patients with main portal vein tumor thrombus.

Tian-Zhu Yu, Wen Zhang, Qing-Xin Liu, Wen-Hui Li, Jing-Qin Ma, Zi-Han Zhang, Min-Jie Yang, Jian-Hua Wang, Bing Chen, Shao-Chong Zeng and 3 more

Abstract read
In one paragraph

Article in Oncotarget, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Hepatic infarction occurred afterJournal of cancer research and clinical oncology · 2024
    Article
  5. Article
  6. Article
  7. Portal Vein Stenting Combined withBioMed research international · 2020
    Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Tian-Zhu YuDepartment of Interventional Radiology, Zhongshan Hospital, Fudan University, Shanghai, China.
Wen ZhangDepartment of Interventional Radiology, Zhongshan Hospital, Fudan University, Shanghai, China.
Qing-Xin LiuDepartment of Interventional Radiology, Zhongshan Hospital, Fudan University, Shanghai, China.
Wen-Hui LiDepartment of Interventional Radiology, Yancheng Third People's Hospital, Southeast University, Yancheng, China.
Jing-Qin MaDepartment of Interventional Radiology, Zhongshan Hospital, Fudan University, Shanghai, China.
Zi-Han ZhangDepartment of Interventional Radiology, Zhongshan Hospital, Fudan University, Shanghai, China.
Min-Jie YangDepartment of Interventional Radiology, Zhongshan Hospital, Fudan University, Shanghai, China.
Jian-Hua WangDepartment of Interventional Radiology, Zhongshan Hospital, Fudan University, Shanghai, China.
Bing ChenDepartment of Radiotherapy, Zhongshan Hospital, Fudan University, Shanghai, China.
Shao-Chong ZengDepartment of Radiotherapy, Zhongshan Hospital, Fudan University, Shanghai, China.
Jian-Jun LuoDepartment of Interventional Radiology, Zhongshan Hospital, Fudan University, Shanghai, China.
Ling-Xiao LiuDepartment of Interventional Radiology, Zhongshan Hospital, Fudan University, Shanghai, China.
Zhi-Ping YanDepartment of Interventional Radiology, Zhongshan Hospital, Fudan University, Shanghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatocellular carcinoma (HCC) patients with main portal vein tumor thrombus have a median survival time of only about 4 months. We therefore compared the safety and efficacy of endovascular brachytherapy (EVBT) and sequential three-dimensional conformal radiotherapy (3-DCRT). From a cohort of 176 patients, we treated 123 with EVBT using iodine-125 seed strands (group A) and the remaining 53 with sequential 3-DCRT (group B). Overall survival, progression free survival and stent patency characteristics were compared between the two groups. Our analysis demonstrated a median survival of 11.7 ± 1.2 months in group A versus 9.5 ± 1.8 months in group B (p = 0.002). The median progression free survival was 5.3 ± 0.7 months in groupA versus 4.4 ± 0.4 months in group B (p = 0.010). The median stent patency period was 10.3 ± 1.1 months in group A versus 8.7 ± 0.7 months in group B (p = 0.003). Therefore, as compared to sequential 3-DCRT, EVBT combined with portal vein stenting and TACE improved overall survival of HCC patients with main portal vein tumor thrombus.

Indexed as

StentsAdultAgedBrachytherapyCarcinoma, HepatocellularChemoembolization, TherapeuticCombined Modality TherapyDisease-Free SurvivalFemaleHumansKaplan-Meier EstimateLiver NeoplasmsMaleMiddle AgedMultivariate AnalysisPortal Veinendovascular brachytherapyhepatocellular carcinomamain portal veinthree-dimensional conformal radiotherapytumor thrombus

Identifiers

PMID28076848
PMCPMC5355329

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.