Evidence map›Paper›PMID 28076820›Full record

ArticleBiophysical journal2017

Probing Conformational Changes during the Gating Cycle of a Potassium Channel in Lipid Bilayers.

Elwin A W van der Cruijsen, Alexander V Prokofyev, Olaf Pongs, Marc Baldus

Open access · bronzeAbstract read
In one paragraph

Article in Biophysical journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 30 citations in OpenAlex.

  1. Simple and rapid TLC blotting-based methodology for screening membrane protein-specific lipids.Analytical sciences : the international journal of the Japan Society for Analytical Chemistry · 2025
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  9. Mechanisms underlying drug-mediated regulation of membrane protein function.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  10. Review
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  12. NMR studies of lipid regulation of the KBiochimica et biophysica acta. Biomembranes · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Elwin A W van der CruijsenNMR Spectroscopy, Bijvoet Center for Biomolecular Research, Utrecht University, Utrecht, The Netherlands.
Alexander V ProkofyevDepartment of Physiology, Institute of Cellular Neurophysiology, University of the Saarland, Homburg, Germany.
Olaf PongsDepartment of Physiology, Institute of Cellular Neurophysiology, University of the Saarland, Homburg, Germany. Electronic address: oupon@t-online.de.
Marc BaldusNMR Spectroscopy, Bijvoet Center for Biomolecular Research, Utrecht University, Utrecht, The Netherlands. Electronic address: m.baldus@uu.nl.
Saarland University · DEUtrecht University · NL

Funding

Synthetic Antigen Binder CoreU54GM087519 · NIGMS · UNIVERSITY OF CHICAGO · PI ZHOU, MING · 2010 to 2017
$31.9M
NIGMS NIH HHS U54 GM087519
6 · The paper itself

Abstract

Ion conduction across the cellular membrane requires the simultaneous opening of activation and inactivation gates of the K

Indexed as

Ion Channel GatingBacterial ProteinsCardiolipinsCell MembraneLipid BilayersModels, MolecularPotassium ChannelsProtein ConformationBacterial ProteinsCardiolipinsLipid BilayersPotassium Channels

Identifiers

PMID28076820
PMCPMC5232892
OpenAlexW2568370273

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.