Evidence map›Paper›PMID 28076631›Full record

ReviewSao Paulo medical journal = Revista paulista de medicina

Targeting stroke risk and improving outcomes in patients with atrial fibrillation in Latin America.

Bruce Stambler, Fernando Scazzuso

Open access · diamondAbstract readReview
In one paragraph

Review in Sao Paulo medical journal = Revista paulista de medicina. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.2field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Atrial fibrillation in the Americas.Lancet regional health. Americas · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Bruce StamblerMD. Director, Cardiac Arrhythmia Research and Education, Piedmont Heart Institute, Atlanta, United States.
Fernando ScazzusoMD. Chief, Department of Electrophysiology, Instituto Cardiovascular de Buenos Aires (ICBA), Buenos Aires, Argentina.
Instituto Cardiovascular de Buenos Aires · ARTexas Cardiac Arrhythmia · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

CONTEXT AND

objective: To examine stroke risk factors, including atrial fibrillation, management and prevention, and stroke outcomes across Latin America. DESIGN AND

setting: Narrative review conducted at Piedmont Heart Institute, United States.

methods: The PubMed, Embase and Cochrane databases were searched for stroke AND "Latin America" AND epidemiology (between January 2009 and March 2015). Further studies in the SciELO, World Health Organization and Pan-American Health Organization databases were used to address specific points.

results: Countries categorized as low or middle-income nations by the World Bank, which includes most of Latin America, account for two-thirds of all strokes. Globally, fewer than half of patients (median treatment level: 43.9%) with atrial fibrillation receive adequate anticoagulation to reduce stroke risk, which correlates with data from Latin America, where 46% of outpatients did not receive guideline-compliant anticoagulation, ranging from 41.8% in Brazil to 54.8% in Colombia.

conclusions: Atrial fibrillation-related stroke carries a heavy burden. Non-vitamin K antagonist oral anti-coagulants provide options for reducing the risk of atrial fibrillation-related stroke. However, cost-effectiveness comparisons with warfarin are warranted before observational health-economics study results can be applied clinically. Initiatives to remedy inequalities and improve access to care across Latin America should accompany risk factor modification and guideline-based prevention.

Indexed as

AnticoagulantsAtrial FibrillationFemaleHumansLatin AmericaMaleRisk AssessmentRisk FactorsStrokeVitamin KAnticoagulantsVitamin K

Identifiers

PMID28076631
PMCPMC11448734
OpenAlexW2567809127

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.