Evidence map›Paper›PMID 28076515›Full record

ArticleClinics (Sao Paulo, Brazil)2016

Serum adipocytokine profile and metabolic syndrome in young adult female dermatomyositis patients.

Marilda Guimarães Silva, Eduardo Ferreira Borba, Suzana Beatriz Veríssimo de Mello, Samuel Katsuyuki Shinjo

Open access · goldAbstract read
In one paragraph

Article in Clinics (Sao Paulo, Brazil), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.

  1. Pooled it
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  12. Adiponectin in Myopathies.International journal of molecular sciences · 2019
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Marilda Guimarães SilvaFaculdade de Medicina da Universidade de São Paulo, Clínica Médica, Reumatologia, São Paulo/SP, Brazil.
Eduardo Ferreira BorbaFaculdade de Medicina da Universidade de São Paulo, Clínica Médica, Reumatologia, São Paulo/SP, Brazil.
Suzana Beatriz Veríssimo de MelloFaculdade de Medicina da Universidade de São Paulo, Clínica Médica, Reumatologia, São Paulo/SP, Brazil.
Samuel Katsuyuki ShinjoFaculdade de Medicina da Universidade de São Paulo, Clínica Médica, Reumatologia, São Paulo/SP, Brazil.
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectives: To analyse the frequency of metabolic syndrome in young adult female dermatomyositis patients and its possible association with clinical and laboratory dermatomyositis-related features and serum adipocytokines.

method: This cross-sectional study included 35 dermatomyositis patients and 48 healthy controls. Metabolic syndrome was defined according to the 2009 Joint Interim Statement.

results: Patient age was comparable in the dermatomyositis and control groups, and the median disease duration was 1.0 year. An increased prevalence of metabolic syndrome was detected in the dermatomyositis group (34.3% vs. 6.3%; p=0.001). In addition, increased serum adiponectin and resistin levels were noted in contrast to lower leptin levels. In dermatomyositis patients, adipocytokine levels were correlated with the levels of total cholesterol, low-density cholesterol, triglycerides and muscle enzymes. A comparison of dermatomyositis patients with (n=12) and without (n=23) syndrome metabolic revealed that adipocytokine levels were also correlated with age, and that dermatomyositis patients with metabolic syndrome tended to have more disease activity despite similar adipocytokine levels.

conclusions: Metabolic syndrome is highly prevalent in young adult female dermatomyositis patients and is related to age and disease activity. Moreover, increased serum adiponectin and resistin levels were detected in dermatomyositis patients, but lower serum leptin levels were observed.

Indexed as

AdipokinesAdultAge of OnsetCase-Control StudiesCholesterolCross-Sectional StudiesDermatomyositisDiabetes MellitusFemaleHumansHypertensionMetabolic SyndromeMuscle, SkeletalReference ValuesRisk FactorsTriglyceridesAdipokinesCholesterolTriglycerides

Identifiers

PMID28076515
PMCPMC5175289
OpenAlexW2568255718

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.