Evidence map›Paper›PMID 28075632›Full record

SynthesisAmerican journal of public health2017

Transgender Population Size in the United States: a Meta-Regression of Population-Based Probability Samples.

Esther L Meerwijk, Jae M Sevelius

4 registry-linked trialsOpen access · greenAbstract readMeta-Analysis
In one paragraph

Synthesis in American journal of public health, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 4 registered trials, which are not on this map. Cited by 294 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
294citing papers in PubMed, 7 pooled it
88.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04838249 recruitingnot on this mapstarted 2021, after this paper: background citation

Investigation of the Effects of Testosterone and Estrogen on Eating Behavior, Metabolism, Energy Balance and Cardiovascular System in Transsexual Patients Undergoing Cross-sex Hormone Therapy

TypeobservationalSponsorUniversity of LeipzigRan2021 to 2026Enrolled80ConditionsTranssexualism, Transgenderism, Adiposity, Eating Behavior
NCT06450405 phase4terminatednot on this mapstarted 2025, after this paper: background citation

Androgen Effects on the Reproductive Neuroendocrine Axis

TypeinterventionalSponsorUniversity of California, San DiegoRan2025 to 2025Enrolled2ConditionsTransgenderism, Reproductive IssuesArmsTestosterone Cypionate 50 MG/ML Injectable Solution
NCT06502353 narecruitingnot on this mapstarted 2025, after this paper: background citation

A Pilot Study to Investigate the Use of the Plexaa Preconditioning Device (BLOOM43) for Gender Affirming Mastectomy - a Prospective Cohort Study

TypeinterventionalSponsorPlexaa LtdRan2025 to 2026Enrolled15ConditionsNipple Necrosis, Nipple Graft LossArmsBLOOM43
NCT07092527 phase4recruitingnot on this mapstarted 2025, after this paper: background citation

Androgen Effects on the Reproductive Neuroendocrine Axis, 2025 Version

TypeinterventionalSponsorUniversity of California, San DiegoRan2025 to 2028Enrolled80ConditionsTransgenderism, Reproductive IssuesArmsTestosterone Cypionate 50 milligrams per millileter (mg/mL) Injectable Solution
3 · Its place in the literature

Who cites it

294 citing papers in PubMed, 7 syntheses or guidelines pooled it, 790 citations in OpenAlex.

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234 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Esther L MeerwijkAt the time of the study, Esther L. Meerwijk was with the Department of Family Health Care Nursing, University of California, San Francisco. Jae M. Sevelius is with the Department of Medicine, University of California, San Francisco.
Jae M SeveliusAt the time of the study, Esther L. Meerwijk was with the Department of Family Health Care Nursing, University of California, San Francisco. Jae M. Sevelius is with the Department of Medicine, University of California, San Francisco.
University of San Francisco · US

Funding

Ujima Mentoring ProgramP30MH062246 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI MALLORY O JOHNSON · 2001 to 2026
$57.4M
NURSING RESEARCH TRAINING IN SYMPTOM MANAGEMENTT32NR007088 · NINR · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI LEE, KATHRYN · 1996 to 2015
$7.5M
NIMH NIH HHS P30 MH062246NINR NIH HHS T32 NR007088
6 · The paper itself

Abstract

backgroundTransgender individuals have a gender identity that differs from the sex they were assigned at birth. The population size of transgender individuals in the United States is not well-known, in part because official records, including the US Census, do not include data on gender identity. Population surveys today more often collect transgender-inclusive gender-identity data, and secular trends in culture and the media have created a somewhat more favorable environment for transgender people.

objectivesTo estimate the current population size of transgender individuals in the United States and evaluate any trend over time. SEARCH

methodsIn June and July 2016, we searched PubMed, Cumulative Index to Nursing and Allied Health Literature, and Web of Science for national surveys, as well as "gray" literature, through an Internet search. We limited the search to 2006 through 2016. SELECTION CRITERIA: We selected population-based surveys that used probability sampling and included self-reported transgender-identity data. DATA COLLECTION AND ANALYSIS: We used random-effects meta-analysis to pool eligible surveys and used meta-regression to address our hypothesis that the transgender population size estimate would increase over time. We used subsample and leave-one-out analysis to assess for bias. MAIN

resultsOur meta-regression model, based on 12 surveys covering 2007 to 2015, explained 62.5% of model heterogeneity, with a significant effect for each unit increase in survey year (F = 17.122; df = 1,10; b = 0.026%; P = .002). Extrapolating these results to 2016 suggested a current US population size of 390 adults per 100 000, or almost 1 million adults nationally. This estimate may be more indicative for younger adults, who represented more than 50% of the respondents in our analysis. AUTHORS'

conclusionsFuture national surveys are likely to observe higher numbers of transgender people. The large variety in questions used to ask about transgender identity may account for residual heterogeneity in our models. Public health implications. Under- or nonrepresentation of transgender individuals in population surveys is a barrier to understanding social determinants and health disparities faced by this population. We recommend using standardized questions to identify respondents with transgender and nonbinary gender identities, which will allow a more accurate population size estimate.

Indexed as

DemographyFemaleGender IdentityHumansMaleProbabilitySurveys and QuestionnairesTransgender PersonsUnited States

Identifiers

PMID28075632
PMCPMC5227946
OpenAlexW2579232716

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.