Evidence map›Paper›PMID 28075370›Full record

ArticleNutrients2017

Effect of Carotenoid Supplemented Formula on Carotenoid Bioaccumulation in Tissues of Infant Rhesus Macaques: A Pilot Study Focused on Lutein.

Sookyoung Jeon, Martha Neuringer, Emily E Johnson, Matthew J Kuchan, Suzette L Pereira, Elizabeth J Johnson, John W Erdman

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.9field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 35 citations in OpenAlex.

  1. Review
  2. Review
  3. Recent advances in carotenoid absorption, distribution, and elimination.Biochimica et biophysica acta. Molecular and cell biology of lipids · 2025
    Review
  4. Article
  5. Fenretinide inhibits vitamin A formation from β-carotene and regulates carotenoid levels in mice.Biochimica et biophysica acta. Molecular and cell biology of lipids · 2022
    Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Nutrition research (New York, N.Y.) · 2019
    Article
  11. Article
  12. Review
  13. Article
  14. Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

Sookyoung JeonDivision of Nutritional Sciences, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA. sjeon17@illinois.edu.
Martha NeuringerOregon National Primate Research Center, Oregon Health and Science University, Beaverton, OR 97239, USA. neuringe@ohsu.edu.
Emily E JohnsonOregon National Primate Research Center, Oregon Health and Science University, Beaverton, OR 97239, USA. johnsemi@ohsu.edu.
Matthew J KuchanAbbott Nutrition, Columbus, OH 43215, USA. matthew.kuchan@abbott.com.
Suzette L PereiraAbbott Nutrition, Columbus, OH 43215, USA. suzette.pereira@abbott.com.
Elizabeth J JohnsonJean Mayer United States Department of Agriculture Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111, USA. Elizabeth.Johnson@tufts.edu.
John W ErdmanDivision of Nutritional Sciences, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA. jwerdman@illinois.edu.
Tufts University · USUniversity of Illinois Urbana-Champaign · USAbbott Nutrition (United States)Abbott (United States) · USOregon Health & Science University · US

Funding

Upgrade of confocal microscopy at the Oregon National Primate Research CenterP51OD011092 · OD · OREGON HEALTH & SCIENCE UNIVERSITY · PI Bonnie J. Nagel · 2012 to 2026
$203.9M
NIH HHS P51 OD011092
6 · The paper itself

Abstract

Lutein is the predominant carotenoid in the developing primate brain and retina, and may have important functional roles. However, its bioaccumulation pattern during early development is not understood. In this pilot study, we investigated whether carotenoid supplementation of infant formula enhanced lutein tissue deposition in infant rhesus macaques. Monkeys were initially breastfed; from 1 to 3 months of age they were fed either a formula supplemented with lutein, zeaxanthin, β-carotene and lycopene, or a control formula with low levels of these carotenoids, for 4 months (

Indexed as

Dietary SupplementsFood, FormulatedAdipose TissueAnimalsAnimals, Newbornbeta CaroteneBrainCarotenoidsChromatography, High Pressure LiquidFemaleLuteinLycopeneMacaca mulattaMalePilot ProjectsRetinabeta CaroteneCarotenoidsLuteinLycopeneZeaxanthinsbioaccumulationbraincarotenoidsformulainfantsluteinretinaRhesus Macaques

Identifiers

PMID28075370
PMCPMC5295095
OpenAlexW2571243083

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.