Evidence map›Paper›PMID 28075368›Full record

ArticleInternational journal of environmental research and public health2017

Critical Windows of Prenatal Exposure to Cadmium and Size at Birth.

Lu Cheng, Bin Zhang, Tongzhang Zheng, Jie Hu, Aifen Zhou, Bryan A Bassig, Wei Xia, David A Savitz, Stephen Buka, Chao Xiong and 12 more

Open access · goldAbstract read
In one paragraph

Article in International journal of environmental research and public health, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
2.9field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 1 synthesis or guideline pooled it, 56 citations in OpenAlex.

  1. Pooled it
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  3. Article
  4. Review
  5. Article
  6. Determination of the effect ofVeterinary research forum : an international quarterly journal · 2025
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  9. Trimester-specific prenatal heavy metal exposures and sex-specific postpartum size and growth.Journal of exposure science & environmental epidemiology · 2023
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Developmental toxicity of cadmium in infants and children: a review.Environmental analysis, health and toxicology · 2021
    Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors at 7 institutions in 2 countries.

Lu ChengKey Laboratory of Environment and Health (HUST), Ministry of Education and Ministry of Environmental Protection, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430000, Hubei, China. chenglu822@hotmail.com.
Bin ZhangKey Laboratory of Environment and Health (HUST), Ministry of Education and Ministry of Environmental Protection, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430000, Hubei, China. mchwhzb@163.com.
Tongzhang ZhengDepartment of Epidemiology, Brown University, Providence, RI 02912, USA. tongzhang_zheng@brown.edu.
Jie HuKey Laboratory of Environment and Health (HUST), Ministry of Education and Ministry of Environmental Protection, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430000, Hubei, China. hujie_tjmu@126.com.
Aifen ZhouWomen and Children Medical and Healthcare Center of Wuhan, Wuhan 430000, Hubei, China. april1972@163.com.
Bryan A BassigDepartment of Environmental Health Sciences, Yale School of Public Health, New Haven, CT 06520, USA. bryan.bassig@nih.gov.
Wei XiaKey Laboratory of Environment and Health (HUST), Ministry of Education and Ministry of Environmental Protection, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430000, Hubei, China. xiawei@hust.edu.cn.
David A SavitzDepartment of Epidemiology, Brown University, Providence, RI 02912, USA. david_savitz@brown.edu.
Stephen BukaDepartment of Epidemiology, Brown University, Providence, RI 02912, USA. stephen_buka@brown.edu.
Chao XiongWomen and Children Medical and Healthcare Center of Wuhan, Wuhan 430000, Hubei, China. xcpopo11@yeah.net.
Joseph M BraunDepartment of Epidemiology, Brown University, Providence, RI 02912, USA. joseph_braun_1@brown.edu.
Yaqi ZhangWomen and Children Medical and Healthcare Center of Wuhan, Wuhan 430000, Hubei, China. cardinal3542@hotmail.com.
Yanqiu ZhouKey Laboratory of Environment and Health (HUST), Ministry of Education and Ministry of Environmental Protection, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430000, Hubei, China. 16483596@life.hkbu.edu.hk.
Xinyun PanKey Laboratory of Environment and Health (HUST), Ministry of Education and Ministry of Environmental Protection, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430000, Hubei, China. panxinyun721@163.com.
Chuansha WuKey Laboratory of Environment and Health (HUST), Ministry of Education and Ministry of Environmental Protection, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430000, Hubei, China. shalovesafin@126.com.
Youjie WangKey Laboratory of Environment and Health (HUST), Ministry of Education and Ministry of Environmental Protection, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430000, Hubei, China. wangyoujie@mails.tjmu.edu.cn.
Zhengmin QianDepartment of Epidemiology, College for Public Health and Social Justice, Saint Louis University, Saint Louis, MO 63103, USA. zqian2@slu.edu.
Aimin YangCollege of Earth and Environmental Science, Lanzhou University, Lanzhou 730000, Gansu, China. aimin_yang@brown.edu.
Megan E RomanoDepartment of Epidemiology, Brown University, Providence, RI 02912, USA. megan_romano@brown.edu.
Kunchong ShiDepartment of Epidemiology, Brown University, Providence, RI 02912, USA. kunchong_shi@brown.edu.
Shunqing XuKey Laboratory of Environment and Health (HUST), Ministry of Education and Ministry of Environmental Protection, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430000, Hubei, China. xust@hust.edu.cn.
Yuanyuan LiKey Laboratory of Environment and Health (HUST), Ministry of Education and Ministry of Environmental Protection, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430000, Hubei, China. liyuanyuan@hust.edu.cn.
Brown University · USHuazhong University of Science and Technology · CNMinistry of Ecology and Environment · CNWuhan Medical Center for Women and Children · CNLanzhou University · CNSaint Louis University · USYale University · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Science/Technical CoreP2CHD041020 · NICHD · BROWN UNIVERSITY · PI ZHENCHAO QIAN · 2016 to 2026
$7.6M
NCATS NIH HHS UL1 TR001863NICHD NIH HHS P2C HD041020
6 · The paper itself

Abstract

Prenatal cadmium (Cd) exposure has been associated with adverse birth outcomes, but the findings of previous studies are inconsistent. We measured Cd concentrations in urine samples at or near 13, 24, and 35 gestational weeks from 282 women in Wuhan, China. We used generalized estimating equation models to assess the associations between maternal creatinine adjusted urinary Cd concentrations at each trimester and birth size. A significant inverse association was observed between higher maternal Cd levels measured during the 1st trimester and birth size in girls. For each log unit increase in Cd (µg/g creatinine) levels from the 1st trimester, there was a decrease in birth weight by 116.99 g (95% confidence interval (CI): -208.87, -25.11 g). The Cd levels from the 1st and 2nd trimesters were also borderline significantly associated with ponderal index in girls. Joint estimation of trimester-specific effects suggested that associations with Cd levels for ponderal index (

Indexed as

AdultBirth WeightCadmiumChinaFemaleFetal DevelopmentHumansInfant, NewbornMaleMaternal ExposurePregnancyPrenatal Exposure Delayed EffectsSex FactorsCadmiumbirth weightcadmiumcritical windowepidemiologyfetal exposure

Identifiers

PMID28075368
PMCPMC5295309
OpenAlexW2568447751

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.