Evidence map›Paper›PMID 28074656›Full record

ArticleThe journal of physical chemistry. B2017

Atomistic Modeling of Ion Conduction through the Voltage-Sensing Domain of the Shaker K

Mona L Wood, J Alfredo Freites, Francesco Tombola, Douglas J Tobias

Abstract read
In one paragraph

Article in The journal of physical chemistry. B, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
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  5. Article
  6. Sodium Channelopathies of Skeletal Muscle.Handbook of experimental pharmacology · 2018
    Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Mona L WoodDepartment of Chemistry, University of California Irvine , Irvine, California 92697-2025, United States.
J Alfredo FreitesDepartment of Chemistry, University of California Irvine , Irvine, California 92697-2025, United States.
Francesco TombolaDepartment of Physiology and Biophysics, University of California Irvine , Irvine, California 92697-4560, United States.
Douglas J TobiasDepartment of Chemistry, University of California Irvine , Irvine, California 92697-2025, United States.ORCID 0000-0002-6971-9828
University of California, Irvine · US

Funding

TrainingP41GM103712 · NIGMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI SEJNOWSKI, TERRENCE J · 2012 to 2021
$16.3M
Mechanisms of Permeation and Gating of Voltage-Sensing DomainsR01GM098973 · NIGMS · UNIVERSITY OF CALIFORNIA-IRVINE · PI TOMBOLA, FRANCESCO · 2011 to 2025
$4.5M
Structure-based design of Hv1 proton channel blockers as potential anti-neoplastiF30CA171717 · NCI · UNIVERSITY OF CALIFORNIA-IRVINE · PI WOOD, MONA · 2013 to 2015
$119k
NCI NIH HHS F30 CA171717NIGMS NIH HHS P41 GM103712NIGMS NIH HHS R01 GM098973
6 · The paper itself

Abstract

Voltage-sensing domains (VSDs) sense changes in the membrane electrostatic potential and, through conformational changes, regulate a specific function. The VSDs of wild-type voltage-dependent K

Indexed as

Molecular Dynamics SimulationElectric ConductivityProtein DomainsShaker Superfamily of Potassium ChannelsShaker Superfamily of Potassium Channels

Identifiers

PMID28074656
PMCPMC5605276
OpenAlexW2576350742

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.