Evidence map›Paper›PMID 28074637›Full record

ArticleBJOG : an international journal of obstetrics and gynaecology2017

Moderately elevated blood pressure during pregnancy and odds of hypertension later in life: the POUCHmoms longitudinal study.

G L Dunietz, K L Strutz, C Holzman, Y Tian, D Todem, B L Bullen, J M Catov

Open access · greenAbstract read
In one paragraph

Article in BJOG : an international journal of obstetrics and gynaecology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
5.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 46 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Article
  5. Blood Pressure and Late Pregnancy Circulating miRNAs in the MADRES Study.Journal of the American Heart Association · 2025
    Article
  6. Review
  7. Maternal Lipids in Pregnancy and Later Life Dyslipidemia: The POUCHmoms Longitudinal Cohort Study.BJOG : an international journal of obstetrics and gynaecology · 2025
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Maternal habitual snoring and blood pressure trajectories in pregnancy.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2022
    Article
  13. Maternal risk of hypertension 7-15 years after pregnancy: clues from the placenta.BJOG : an international journal of obstetrics and gynaecology · 2021
    Article
  14. Dietary sodium, potassium, and blood pressure in normotensive pregnant women: the National Health and Nutrition Examination Survey.Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme · 2020
    Article
  15. Review
  16. Review
  17. Observational
  18. Article
  19. Article
  20. Pregnancy as a Window to Racial Disparities in Hypertension.Journal of women's health (2002) · 2019
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

G L DunietzDepartment of Neurology and Sleep Disorders Center, University of Michigan, Ann Arbor, MI, USA.
K L StrutzDepartment of Public Health, Grand Valley State University, Grand Rapids, MI, USA.
C HolzmanDepartment of Epidemiology and Biostatistics, Michigan State University, East Lansing, MI, USA.
Y TianDepartment of Epidemiology and Biostatistics, Michigan State University, East Lansing, MI, USA.
D TodemDepartment of Epidemiology and Biostatistics, Michigan State University, East Lansing, MI, USA.
B L BullenDepartment of Epidemiology and Biostatistics, Michigan State University, East Lansing, MI, USA.
J M CatovDepartments of Obstetrics, Gynecology & Reproductive Sciences and of Epidemiology, University of Pittsburgh, Pittsburgh, PA, USA.
Michigan State University · USGrand Valley State University · USMichigan Medicine · USUniversity of Pittsburgh · US

Funding

TRAINING IN CLINICAL AND BASIC NEUROSCIENCET32NS007222 · NINDS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Henry L Paulson · 1985 to 2026
$8.0M
Etiologic Heterogeneity in Preterm DeliveryR01HD034543 · NICHD · MICHIGAN STATE UNIVERSITY · PI HOLZMAN, CLAUDIA B. · 1997 to 2005
$5.3M
Preterm Delivery and Maternal Cardiovascular Disease RiskR01HL103825 · NHLBI · MICHIGAN STATE UNIVERSITY · PI CATOV, JANET M, HOLZMAN, CLAUDIA B. · 2010 to 2013
$3.6M
Training Program in Perinatal EpidemiologyT32HD046377 · NICHD · MICHIGAN STATE UNIVERSITY · PI PANETH, NIGEL SEFTON · 2005 to 2014
$2.5M
Immune System Gene Polymorphisms and Preterm DeliveryU01DP000143 · DP · MICHIGAN STATE UNIVERSITY · PI HOLZMAN, CLAUDIA B. · 2005 to 2009
$2.1M
NCCDPHP CDC HHS U01 DP000143NHLBI NIH HHS R01 HL103825NICHD NIH HHS R01 HD034543NICHD NIH HHS T32 HD046377NINDS NIH HHS T32 NS007222
6 · The paper itself

Abstract

objectiveHypertensive disorders in pregnancy signal an increased risk of cardiovascular disease for women. However, future hypertension risk among pregnant women with moderately elevated blood pressure (BP) is unknown. We examined associations among moderately elevated BP or hypertensive disorders during pregnancy and later prehypertension or hypertension.

designLongitudinal cohort study.

settingFive communities in Michigan, USA. SAMPLE: Data are from pregnant women enrolled in the Pregnancy Outcomes and Community Health Study. We included 667 women with gestational BP measurements who participated in the POUCHmoms Study follow-up 7-15 years later.

methodsModerately elevated BP was defined as two measures of systolic BP ≥ 120 mmHg or diastolic BP ≥80 mmHg among women without a hypertensive disorder. Weighted multinomial logistic regression models estimated odds of prehypertension or hypertension at follow-up, adjusted for maternal confounders and time to follow-up.

main outcome measuresPrehypertension or hypertension.

resultsWomen meeting the moderately elevated BP criteria (64%) had significantly higher odds of hypertension at follow-up (adjusted odds ratio 2.6; 95% confidence interval 1.2-5.5). These increased odds were observed for moderately elevated BP first identified before or after 20 weeks of gestation, and for elevated systolic BP alone or combined with elevated diastolic BP.

conclusionsModerately elevated BP in pregnancy may be a risk factor for future hypertension. Pregnancy offers an opportunity to identify women at risk for hypertension who may not have been identified otherwise. TWEETABLE ABSTRACT: Moderately elevated blood pressure in pregnancy may be associated with hypertension later in life.

Indexed as

Pregnancy Complications, CardiovascularAdultBlood PressureFemaleFollow-Up StudiesHumansHypertensionLogistic ModelsLongitudinal StudiesMichiganOdds RatioPregnancyPrehypertensionRisk FactorsYoung AdultBlood pressurediastolic pressurehypertensionpregnancyprehypertensionsystolic pressure

Identifiers

PMID28074637
PMCPMC5505807
OpenAlexW2577056231

What OpenQuestion holds

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LicenceTDM
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.