Evidence map›Paper›PMID 28074345›Full record

ReviewSports medicine - open2017

The Beneficial Effects of Physical Activity: Is It Down to Your Genes? A Systematic Review and Meta-Analysis of Twin and Family Studies.

J R Zadro, D Shirley, T B Andrade, K J Scurrah, A Bauman, P H Ferreira

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Sports medicine - open, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 2 pooled it
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 49 citations in OpenAlex.

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  14. Genetic approaches toward understanding the individual variation in cardiac structure, function and responses to exercise training.The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology · 2021
    Review
  15. Heritability and Environmental Correlation of Phase Angle with Anthropometric Measurements: A Twin Study.International journal of environmental research and public health · 2020
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

J R ZadroDiscipline of Physiotherapy, Faculty of Health Sciences, The University of Sydney, 75 East Street, Lidcombe, Sydney, NSW 1825, Australia. jzad3326@uni.sydney.edu.au.
D ShirleyDiscipline of Physiotherapy, Faculty of Health Sciences, The University of Sydney, 75 East Street, Lidcombe, Sydney, NSW 1825, Australia.
T B AndradeDiscipline of Physiotherapy, Faculty of Health Sciences, The University of Sydney, 75 East Street, Lidcombe, Sydney, NSW 1825, Australia.
K J ScurrahAustralian Centre for Excellence in Twin Research, Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Australia.
A BaumanSchool of Public Health and Charles Perkins Centre, University of Sydney, Sydney, Australia.
P H FerreiraDiscipline of Physiotherapy, Faculty of Health Sciences, The University of Sydney, 75 East Street, Lidcombe, Sydney, NSW 1825, Australia.
University of Sydney · AUUniversity of Melbourne · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThere is evidence for considerable heterogeneity in the responsiveness to regular physical activity (PA) which might reflect the influence of genetic factors. The aim of this systematic review was to assess whether the response to a PA intervention for measures of body composition and cardiorespiratory fitness is (i) correlated within twin pairs and/or families and (ii) more correlated in monozygotic twins (MZ) compared to dizygotic twins (DZ), which would be consistent with genetic effects.

methodsWe performed electronic database searches, combining key words relating to "physical activity" and "genetics", in MEDLINE, CINAHL, EMBASE, SPORTS Discuss, AMED, PsycINFO, WEB OF SCIENCE, and SCOPUS from the earliest records to March 2016. Twin and family studies were included if they assessed body composition and/or cardiorespiratory fitness following a PA intervention, and provided a heritability estimate, maximal heritability estimate, or within MZ twin pair correlation (r

resultsAfter screening 224 full texts, nine twin and five family studies were included in this review. The pooled r

conclusionsShared familial factors, including genetics, are likely to be a significant contributor to the response of body composition and cardiorespiratory fitness following PA. Genetic factors may explain individual variation in the response to PA. TRIAL REGISTRATIONS: PROSPERO Registration No CRD42015020056 .

Indexed as

Body compositionCardiorespiratory fitnessFamilial aggregationGeneticsHeritabilityPhysical activity

Identifiers

PMID28074345
PMCPMC5225201
OpenAlexW2570086743

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.