Evidence map›Paper›PMID 28074269›Full record

ArticleInternational archives of occupational and environmental health2017

Varied exposure to carcinogenic, mutagenic, and reprotoxic (CMR) chemicals in occupational settings in France.

Nathalie Havet, Alexis Penot, Magali Morelle, Lionel Perrier, Barbara Charbotel, Béatrice Fervers

Abstract read
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In one paragraph

Article in International archives of occupational and environmental health, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Occupational Risk Factors by Sectors: An Observational Study of 20,000 Workers.International journal of environmental research and public health · 2023
    Observational
  3. Article
  4. Article
  5. Article
  6. MiXie, an Online Tool for Better Health Assessment of Workers Exposed to Multiple Chemicals.International journal of environmental research and public health · 2022
    Article
  7. Article
  8. Systematic screening for occupations and occupational exposures in head and neck squamous cell carcinoma patients.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2019
    Article
  9. Article
  10. Occupational determinants of health.International public health journal
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Nathalie HavetUniversité Claude Bernard Lyon 1, ISFA, Laboratoire SAF, Université de Lyon, 50 Avenue Tony Garnier, 69007, Lyon, France. nathalie.havet@univ-lyon1.fr.
Alexis PenotENS Lyon, GATE-UMR 5824-CNRS, Université de Lyon, 15 parvis René Descartes, BP 7000, 69347, Lyon Cedex 7, France.
Magali MorelleCancer Centre Léon Bérard, Direction de la Recherche Clinique et de l'innovation, GATE - UMR 5824-CNRS, Université de Lyon, 28 rue Laënnec, 69373, Lyon Cedex 08, France.
Lionel PerrierCancer Centre Léon Bérard, Direction de la Recherche Clinique et de l'innovation, GATE - UMR 5824-CNRS, Université de Lyon, 28 rue Laënnec, 69373, Lyon Cedex 08, France.
Barbara CharbotelUniversité Claude Bernard Lyon 1, IFSTTAR, UMRESTTE, Centre Hospitalier Lyon Sud Service des maladies professionnelles, Hospices Civils de Lyon, Université de Lyon, 8 avenue Rockefeller, 69373, Lyon Cedex 08, France.
Béatrice FerversDepartment Cancer and Environment, Université de Lyon, Centre Léon Bérard, 28 rue Laënnec, 69373, Lyon Cedex 08, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo explore varied exposure to carcinogenic, mutagenic, and reprotoxic chemicals (CMR) for French employees.

methodsOur study assessed data from the French national cross-sectional survey of occupational risks (SUMER) that was conducted in 2010 in a national representative sample of employees. We selected 28 CMR agents that were classified by the International Agency for Research on Cancer or European Union as being known or presumed to have CMR potential in humans. The association of individual and job characteristics with exposure prevalence, duration, and intensity of the CMR agents during a 1-week period was examined using multilevel logistic regression analysis.

resultsOverall, 10.4% of employees in 2010 were exposed to one or more CMR agents at their workplace, and 3.4% were subjected to multiple CMR exposures. Blue-collar workers, night-shift workers and workers with short-term employment contracts experienced higher exposure prevalence (p < 0.01) and intensity (p < 0.05). Blue-collar workers and shift workers experienced also longer exposure duration (p < 0.001). Conversely, managers, workers of large companies, and women were less exposed to CMR agents (p < 0.001). The presence of a Committee for Health, Safety, and Working Conditions, and intervention by Occupational Health and Safety officers were significantly associated with reduced exposure intensities (p < 0.001 and p < 0.05). Establishment of European CMR regulations and the existence of an applicable substitution principle reduced the exposure duration (p < 0.001) and intensity (p < 0.05).

conclusionsOur results point out disparities in CMR exposure and identify high-priority targets for prevention measures to help reducing social health discrepancies.

Indexed as

CarcinogensHazardous SubstancesMutagensAdolescentAdultCross-Sectional StudiesFemaleFranceHumansLogistic ModelsMaleMiddle AgedOccupational ExposureCarcinogensHazardous SubstancesMutagensCarcinogenicHealth inequalitiesMutagenicOccupational exposureReprotoxic chemicals

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.