Evidence map›Paper›PMID 28074113›Full record

ArticleGenes and environment : the official journal of the Japanese Environmental Mutagen Society2017

Genetic polymorphisms of human cytochrome P450 CYP1A1 in an Egyptian population and tobacco-induced lung cancer.

Nada Ezzeldin, Dalia El-Lebedy, Amira Darwish, Ahmed El-Bastawisy, Mirhane Hassan, Shereen Abd El-Aziz, Mohamed Abdel-Hamid, Amal Saad-Hussein

Open access · goldAbstract read
In one paragraph

Article in Genes and environment : the official journal of the Japanese Environmental Mutagen Society, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 30 citations in OpenAlex.

  1. Review
  2. Article
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  4. An epigenetic memory at thebioRxiv : the preprint server for biology · 2024
    Article
  5. Review
  6. Article
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  14. Molecular epidemiology; New but impressive.Medical journal of the Islamic Republic of Iran · 2018
    Article
  15. Association of CytochromeFrontiers in public health · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Nada EzzeldinChest Diseases, National Research Center, Cairo, Egypt.
Dalia El-LebedyDepartment of Clinical and Chemical Pathology, National Research Center, Cairo, Egypt.
Amira DarwishMedical Oncology, National Cancer Institute, Cairo University, Cairo, Egypt.
Ahmed El-BastawisyMedical Oncology, National Cancer Institute, Cairo University, Cairo, Egypt.
Mirhane HassanDepartment of Clinical and Chemical Pathology, National Research Center, Cairo, Egypt.
Shereen Abd El-AzizDepartment of Clinical and Chemical Pathology, National Research Center, Cairo, Egypt.
Mohamed Abdel-HamidMedical Molecular Genetics, National Research Center, Cairo, Egypt.
Amal Saad-HusseinDepartment of Environmental Health and Preventive Medicine, National Research Center, Cairo, Egypt.
National Water Research Center · EGCairo University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCytochrome P450 CYP1A1 helps detoxify the potential carcinogens in tobacco smoke, it was reported that polymorphisms in the coding gene result in variation in the expression and activity levels which alter metabolism and clearance of carcinogens and therefore modify cancer risk. In this work, we aimed to identify

methodsA case-control study was conducted on 150 unrelated lung cancer patients and 150 unrelated control subjects. Genomic DNA was extracted and sequencing analysis of

resultsThree variants in

conclusionOur findings support that

Indexed as

CYP1A1Lung cancerPolymorphismsTobacco smoking

Identifiers

PMID28074113
PMCPMC5219678
OpenAlexW2569278986

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.