Evidence map›Paper›PMID 28074089›Full record

ReviewThe journal of venomous animals and toxins including tropical diseases2017

Antiviral activity of animal venom peptides and related compounds.

Élida Cleyse Gomes da Mata, Caroline Barbosa Farias Mourão, Marisa Rangel, Elisabeth Ferroni Schwartz

Abstract readReview
In one paragraph

Review in The journal of venomous animals and toxins including tropical diseases, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

52 citing papers in PubMed.

  1. Article
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  10. Characterization ofFrontiers in pharmacology · 2025
    Article
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  12. Review
  13. Article
  14. Biochemical Characterisation andTropical life sciences research · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Élida Cleyse Gomes da MataLaboratory of Toxinology, Department of Physiological Sciences, University of Brasília, Brasília, DF 70910-900 Brazil.
Caroline Barbosa Farias MourãoLaboratory of Toxinology, Department of Physiological Sciences, University of Brasília, Brasília, DF 70910-900 Brazil.
Marisa RangelLaboratory of Toxinology, Department of Physiological Sciences, University of Brasília, Brasília, DF 70910-900 Brazil ; Laboratory of Immunopathology, Butantan Institute, São Paulo, SP 05508-900 Brazil.
Elisabeth Ferroni SchwartzLaboratory of Toxinology, Department of Physiological Sciences, University of Brasília, Brasília, DF 70910-900 Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Viruses exhibit rapid mutational capacity to trick and infect host cells, sometimes assisted through virus-coded peptides that counteract host cellular immune defense. Although a large number of compounds have been identified as inhibiting various viral infections and disease progression, it is urgent to achieve the discovery of more effective agents. Furthermore, proportionally to the great variety of diseases caused by viruses, very few viral vaccines are available, and not all are efficient. Thus, new antiviral substances obtained from natural products have been prospected, including those derived from venomous animals. Venoms are complex mixtures of hundreds of molecules, mostly peptides, that present a large array of biological activities and evolved to putatively target the biochemical machinery of different pathogens or host cellular structures. In addition, non-venomous compounds, such as some body fluids of invertebrate organisms, exhibit antiviral activity. This review provides a panorama of peptides described from animal venoms that present antiviral activity, thereby reinforcing them as important tools for the development of new therapeutic drugs.

Indexed as

Amphibian venomAntiretroviral agentsAntiviral agentsHIVInsect venomMarine animal peptidesScorpion venomSnake venom

Identifiers

PMID28074089
PMCPMC5217322

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.